Regulation of MAVS Expression and Signaling Function in the Antiviral Innate Immune Response

Regulation of MAVS Expression and Signaling Function in the Antiviral Innate Immune Response

Viral infection is controlled by host innate immune cells that express specialized receptors for viral components. Engagement of these pattern recognition receptors triggers a series of signaling pathways that culminate in the production of antiviral mediators such as type I interferons. Mitochondri...

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Bibliographic Details
Main Authors: Zhihua Ren, Ting Ding, Zhicai Zuo, Zhiwen Xu, Junliang Deng, Zhanyong Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
innate immunity
MAVS
molecular regulation
viral replication
immune evasion
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01030/full

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