Single-cell transcriptomic analysis reveals tumor cell heterogeneity and immune microenvironment features of pituitary neuroendocrine tumors

Single-cell transcriptomic analysis reveals tumor cell heterogeneity and immune microenvironment features of pituitary neuroendocrine tumors

Abstract Background Pituitary neuroendocrine tumors (PitNETs) are one of the most common types of intracranial tumors. Currently, the cellular characteristics of normal pituitary and various other types of PitNETs are still not completely understood. Methods We performed single-cell RNA sequencing (...

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Bibliographic Details
Main Authors: Nan Yan, Weiyan Xie, Dongfang Wang, Qiuyue Fang, Jing Guo, Yiyuan Chen, Xinqi Li, Lei Gong, Jialin Wang, Wenbo Guo, Xuegong Zhang, Yazhuo Zhang, Jin Gu, Chuzhong Li
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Genome Medicine
Subjects:
Pituitary neuroendocrine tumor
Tumor heterogeneity
Tumor microenvironment
Single-cell RNA sequencing
Online Access:https://doi.org/10.1186/s13073-023-01267-3

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