A Unique Sequence Is Essential for Efficient Multidrug Efflux Function of the MtrD Protein of <italic toggle="yes">Neisseria gonorrhoeae</italic>

A Unique Sequence Is Essential for Efficient Multidrug Efflux Function of the MtrD Protein of <italic toggle="yes">Neisseria gonorrhoeae</italic>

ABSTRACT Antimicrobial resistance in Neisseria gonorrhoeae has reached an alarming level, severely impacting the effective treatment of gonorrhea. Belonging to the resistance-nodulation-cell division (RND) superfamily of efflux transporters, the MtrD membrane protein of N. gonorrhoeae provides resis...

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Bibliographic Details
Main Authors: Mohsen Chitsaz, Vrinda Gupta, Benjamin Harris, Megan L. O’Mara, Melissa H. Brown
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mBio
Subjects:
RND protein
efflux pump
Neisseria gonorrhoeae
gonorrhea
multidrug resistance
MtrD protein
Online Access:https://journals.asm.org/doi/10.1128/mBio.01675-21

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