In a Heartbeat: Light and Cardiovascular Physiology
Light impinging on the retina fulfils a dual function: it serves for vision and it is required for proper entrainment of the endogenous circadian timing system to the 24-h day, thus influencing behaviors that promote health and optimal quality of life but are independent of image formation. The circ...
| Главные авторы: | , , |
|---|---|
| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Frontiers Media S.A.
2017-10-01
|
| Серии: | Frontiers in Neurology |
| Предметы: | |
| Online-ссылка: | http://journal.frontiersin.org/article/10.3389/fneur.2017.00541/full |
| _version_ | 1828808341844918272 |
|---|---|
| author | Sarah L. Chellappa Sarah L. Chellappa Ruta Lasauskaite Christian Cajochen |
| author_facet | Sarah L. Chellappa Sarah L. Chellappa Ruta Lasauskaite Christian Cajochen |
| author_sort | Sarah L. Chellappa |
| collection | DOAJ |
| description | Light impinging on the retina fulfils a dual function: it serves for vision and it is required for proper entrainment of the endogenous circadian timing system to the 24-h day, thus influencing behaviors that promote health and optimal quality of life but are independent of image formation. The circadian pacemaker located in the suprachiasmatic nuclei modulates the cardiovascular system with an intrinsic ability to anticipate morning solar time and with a circadian nature of adverse cardiovascular events. Here, we infer that light exposure might affect cardiovascular function and provide evidence from existing research. Findings show a time-of-day dependent increase in relative sympathetic tone associated with bright light in the morning but not in the evening hours. Furthermore, dynamic light in the early morning hours can reduce the deleterious sleep-to-wake evoked transition on cardiac modulation. On the contrary, effects of numerous light parameters, such as illuminance level and wavelength of monochromatic light, on cardiac function are mixed. Therefore, in future research studies, light modalities, such as timing, duration, and its wavelength composition, should be taken in to account when testing the potential of light as a non-invasive countermeasure for adverse cardiovascular events. |
| first_indexed | 2024-12-12T08:40:16Z |
| format | Article |
| id | doaj.art-08de848c657f45faaa80f7abcb15c195 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-12T08:40:16Z |
| publishDate | 2017-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-08de848c657f45faaa80f7abcb15c1952022-12-22T00:30:49ZengFrontiers Media S.A.Frontiers in Neurology1664-22952017-10-01810.3389/fneur.2017.00541303033In a Heartbeat: Light and Cardiovascular PhysiologySarah L. Chellappa0Sarah L. Chellappa1Ruta Lasauskaite2Christian Cajochen3Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United StatesDivision of Sleep Medicine, Harvard Medical School, Boston, MA, United StatesCentre for Chronobiology, Psychiatric Hospital of the University of Basel, Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, Basel, SwitzerlandCentre for Chronobiology, Psychiatric Hospital of the University of Basel, Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, Basel, SwitzerlandLight impinging on the retina fulfils a dual function: it serves for vision and it is required for proper entrainment of the endogenous circadian timing system to the 24-h day, thus influencing behaviors that promote health and optimal quality of life but are independent of image formation. The circadian pacemaker located in the suprachiasmatic nuclei modulates the cardiovascular system with an intrinsic ability to anticipate morning solar time and with a circadian nature of adverse cardiovascular events. Here, we infer that light exposure might affect cardiovascular function and provide evidence from existing research. Findings show a time-of-day dependent increase in relative sympathetic tone associated with bright light in the morning but not in the evening hours. Furthermore, dynamic light in the early morning hours can reduce the deleterious sleep-to-wake evoked transition on cardiac modulation. On the contrary, effects of numerous light parameters, such as illuminance level and wavelength of monochromatic light, on cardiac function are mixed. Therefore, in future research studies, light modalities, such as timing, duration, and its wavelength composition, should be taken in to account when testing the potential of light as a non-invasive countermeasure for adverse cardiovascular events.http://journal.frontiersin.org/article/10.3389/fneur.2017.00541/fulllightnon-image-forming systemcircadian rhythmscardiovascular physiologyheart rate variability |
| spellingShingle | Sarah L. Chellappa Sarah L. Chellappa Ruta Lasauskaite Christian Cajochen In a Heartbeat: Light and Cardiovascular Physiology Frontiers in Neurology light non-image-forming system circadian rhythms cardiovascular physiology heart rate variability |
| title | In a Heartbeat: Light and Cardiovascular Physiology |
| title_full | In a Heartbeat: Light and Cardiovascular Physiology |
| title_fullStr | In a Heartbeat: Light and Cardiovascular Physiology |
| title_full_unstemmed | In a Heartbeat: Light and Cardiovascular Physiology |
| title_short | In a Heartbeat: Light and Cardiovascular Physiology |
| title_sort | in a heartbeat light and cardiovascular physiology |
| topic | light non-image-forming system circadian rhythms cardiovascular physiology heart rate variability |
| url | http://journal.frontiersin.org/article/10.3389/fneur.2017.00541/full |
| work_keys_str_mv | AT sarahlchellappa inaheartbeatlightandcardiovascularphysiology AT sarahlchellappa inaheartbeatlightandcardiovascularphysiology AT rutalasauskaite inaheartbeatlightandcardiovascularphysiology AT christiancajochen inaheartbeatlightandcardiovascularphysiology |