Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective Study
Introduction Flow diversion (FD) has emerged as an effective treatment option for intracranial aneurysms (IAs). However, there is limited evidence regarding its safety and efficacy specifically for distal aneurysms of the posterior circulation including posterior inferior cerebellar artery (PICA), a...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-11-01
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| Series: | Stroke: Vascular and Interventional Neurology |
| Online Access: | https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.170 |
| _version_ | 1797221186555346944 |
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| author | Mahmoud Dibas Juan Vivanco‐Suarez Aaron Rodriguez‐Calienes Ricardo A. Hanel Gabor Toth Milagros Galecio‐Castillo Vitor M. Pereira David Altschul Cristian Alva Johanna T. Fifi Peter T. Kan Ajit S. Puri Ajay K. Wakhloo Priyank Khandelwal Mudassir Farooqui Santiago Ortega‐Gutierrez |
| author_facet | Mahmoud Dibas Juan Vivanco‐Suarez Aaron Rodriguez‐Calienes Ricardo A. Hanel Gabor Toth Milagros Galecio‐Castillo Vitor M. Pereira David Altschul Cristian Alva Johanna T. Fifi Peter T. Kan Ajit S. Puri Ajay K. Wakhloo Priyank Khandelwal Mudassir Farooqui Santiago Ortega‐Gutierrez |
| author_sort | Mahmoud Dibas |
| collection | DOAJ |
| description | Introduction Flow diversion (FD) has emerged as an effective treatment option for intracranial aneurysms (IAs). However, there is limited evidence regarding its safety and efficacy specifically for distal aneurysms of the posterior circulation including posterior inferior cerebellar artery (PICA), anterior inferior cerebellar artery (AICA), superior cerebellar artery (SCA), and the P2 and P3 segment of the posterior cerebral artery (PCA). This study aimed to investigate the outcomes of FD for these aneurysms. Methods A retrospective analysis of a multicentric observational registry was performed between 2014 and 2022. Patients harboring distal aneurysms of the posterior circulation including the PICA, AICA, SCA, and PCA P2‐3 treated with FD were included. Aneurysms characteristics and outcomes were calculated for the total series and a comparison was performed between fusiform/dissecting versus saccular aneurysms. The primary outcome was complete occlusion at last imaging follow up which was defined as per the Raymond Roy occlusion scale. Additional outcomes included the retreatment rate, and thromboembolic and hemorrhagic complications Results Overall, 36 patients with 36 aneurysms were treated with FD with a median age in years of 60.0 (interquartile range [IQR]: 52.8‐65.3 years). Of those, 13 were fusiform/dissecting while 23 were saccular IAs. Complete occlusion was achieved in 78.1% for all IAs at a median follow‐up of 14.0 months (IQR: 9.3‐48.6 months). There was no significant difference in rates of complete occlusion between fusiform/dissecting (91.7%) and saccular aneurysms (70%, p=0.151). Thromboembolic and hemorrhagic complications were observed in four cases (11.1%), and retreatment was required for four IAs (11.4%). There was no significant difference in rates of thromboembolic and hemorrhagic complications, or retreatment between fusiform/dissecting and saccular IAs Conclusion This study suggests the safety and efficacy of FD for distal aneurysms of the posterior circulation. Further larger‐scale studies are warranted to confirm these findings and to explore the long‐term safety and efficacy of FD in this specific aneurysm population. |
| first_indexed | 2024-03-07T15:38:15Z |
| format | Article |
| id | doaj.art-08dfbd773d5f470582ee8cc8fc42caae |
| institution | Directory Open Access Journal |
| issn | 2694-5746 |
| language | English |
| last_indexed | 2024-04-24T13:01:26Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke: Vascular and Interventional Neurology |
| spelling | doaj.art-08dfbd773d5f470582ee8cc8fc42caae2024-04-05T10:51:56ZengWileyStroke: Vascular and Interventional Neurology2694-57462023-11-013S210.1161/SVIN.03.suppl_2.170Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective StudyMahmoud Dibas0Juan Vivanco‐Suarez1Aaron Rodriguez‐Calienes2Ricardo A. Hanel3Gabor Toth4Milagros Galecio‐Castillo5Vitor M. Pereira6David Altschul7Cristian Alva8Johanna T. Fifi9Peter T. Kan10Ajit S. Puri11Ajay K. Wakhloo12Priyank Khandelwal13Mudassir Farooqui14Santiago Ortega‐Gutierrez15Department of Neurology University of Iowa Hospitals and Clinics Iowa United StatesDepartment of Neurology University of Iowa Hospitals and Clinics Iowa United StatesDepartment of Neurology University of Iowa Hospitals and Clinics Iowa United StatesLyerly Neurosurgery Baptist Neurological Institute Jacksonville FL USACerebrovascular Center Neurological Institute Cleveland Clinic Ohio United StatesDepartment of Neurology University of Iowa Hospitals and Clinics Iowa United StatesDepartment of Neurosurgery St Michael's Hospital Toronto Ontario CanadaDepartment of Neurological Surgery Montefiore Medical Center Albert Einstein College of Medicine New York United StatesDepartment of Neurology University of Iowa Hospitals and Clinics Iowa United StatesDepartment of Neurological Surgery Mount Sinai Health System New York United StatesDepartment of Neurosurgery The University of Texas Medical Branch Texas United StatesDepartment of Radiology Division of Neurointerventional Radiology University of Massachusetts Chan Medical School Massachusetts United StatesNeurointerventional Radiology and Radiology Lahey Hospital and Medical Center Massachusetts United StateDepartment of Neurological Surgery New Jersey Medical School RUTGERS New Jersey United StatesDepartment of Neurology University of Iowa Hospitals and Clinics Iowa United StatesDepartment of Neurology Neurosurgery & Radiology University of Iowa Hospitals and Clinics Iowa United StatesIntroduction Flow diversion (FD) has emerged as an effective treatment option for intracranial aneurysms (IAs). However, there is limited evidence regarding its safety and efficacy specifically for distal aneurysms of the posterior circulation including posterior inferior cerebellar artery (PICA), anterior inferior cerebellar artery (AICA), superior cerebellar artery (SCA), and the P2 and P3 segment of the posterior cerebral artery (PCA). This study aimed to investigate the outcomes of FD for these aneurysms. Methods A retrospective analysis of a multicentric observational registry was performed between 2014 and 2022. Patients harboring distal aneurysms of the posterior circulation including the PICA, AICA, SCA, and PCA P2‐3 treated with FD were included. Aneurysms characteristics and outcomes were calculated for the total series and a comparison was performed between fusiform/dissecting versus saccular aneurysms. The primary outcome was complete occlusion at last imaging follow up which was defined as per the Raymond Roy occlusion scale. Additional outcomes included the retreatment rate, and thromboembolic and hemorrhagic complications Results Overall, 36 patients with 36 aneurysms were treated with FD with a median age in years of 60.0 (interquartile range [IQR]: 52.8‐65.3 years). Of those, 13 were fusiform/dissecting while 23 were saccular IAs. Complete occlusion was achieved in 78.1% for all IAs at a median follow‐up of 14.0 months (IQR: 9.3‐48.6 months). There was no significant difference in rates of complete occlusion between fusiform/dissecting (91.7%) and saccular aneurysms (70%, p=0.151). Thromboembolic and hemorrhagic complications were observed in four cases (11.1%), and retreatment was required for four IAs (11.4%). There was no significant difference in rates of thromboembolic and hemorrhagic complications, or retreatment between fusiform/dissecting and saccular IAs Conclusion This study suggests the safety and efficacy of FD for distal aneurysms of the posterior circulation. Further larger‐scale studies are warranted to confirm these findings and to explore the long‐term safety and efficacy of FD in this specific aneurysm population.https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.170 |
| spellingShingle | Mahmoud Dibas Juan Vivanco‐Suarez Aaron Rodriguez‐Calienes Ricardo A. Hanel Gabor Toth Milagros Galecio‐Castillo Vitor M. Pereira David Altschul Cristian Alva Johanna T. Fifi Peter T. Kan Ajit S. Puri Ajay K. Wakhloo Priyank Khandelwal Mudassir Farooqui Santiago Ortega‐Gutierrez Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective Study Stroke: Vascular and Interventional Neurology |
| title | Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective Study |
| title_full | Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective Study |
| title_fullStr | Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective Study |
| title_full_unstemmed | Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective Study |
| title_short | Abstract 170: Flow Diversion for Distal Aneurysms of the Posterior Circulation: A Multicenter Retrospective Study |
| title_sort | abstract 170 flow diversion for distal aneurysms of the posterior circulation a multicenter retrospective study |
| url | https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.170 |
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