Discovery of Novel Pleuromutilin Derivatives as Potent Antibacterial Agents for the Treatment of MRSA Infection
A series of novel pleuromutilin derivatives containing nitrogen groups on the side chain of C14 were synthesized under mild conditions. Most of the synthesized derivatives displayed potent antibacterial activities. Compound <b>9</b> was found to be the most active antibacterial derivativ...
Auteurs principaux: | Han-Qing Fang, Jie Zeng, Shou-Kai Wang, Xiao Wang, Fang Chen, Bo Li, Jie Liu, Zhen Jin, Ya-Hong Liu, You-Zhi Tang |
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Format: | Article |
Langue: | English |
Publié: |
MDPI AG
2022-01-01
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Collection: | Molecules |
Sujets: | |
Accès en ligne: | https://www.mdpi.com/1420-3049/27/3/931 |
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