Discovery of Novel Pleuromutilin Derivatives as Potent Antibacterial Agents for the Treatment of MRSA Infection

A series of novel pleuromutilin derivatives containing nitrogen groups on the side chain of C14 were synthesized under mild conditions. Most of the synthesized derivatives displayed potent antibacterial activities. Compound <b>9</b> was found to be the most active antibacterial derivativ...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Han-Qing Fang, Jie Zeng, Shou-Kai Wang, Xiao Wang, Fang Chen, Bo Li, Jie Liu, Zhen Jin, Ya-Hong Liu, You-Zhi Tang
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2022-01-01
Цуврал:Molecules
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/1420-3049/27/3/931