Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)

Bibliographic Details
Main Authors: Humraaz Samra, Katherin Leckie, Leni Moldovan, Kristen Wanczyk, Lava Timsina, Mithun Sinha, Imran Khan Mohammed, Ravi Mylvaganam, Anush Motaganahalli, Paul Territo, Ashley Gutwein, Raghunandan Motaganahalli, Michael P. Murphy
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:JVS - Vascular Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350323000639
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author Humraaz Samra
Katherin Leckie
Leni Moldovan
Kristen Wanczyk
Lava Timsina
Mithun Sinha
Imran Khan Mohammed
Ravi Mylvaganam
Anush Motaganahalli
Paul Territo
Ashley Gutwein
Raghunandan Motaganahalli
Michael P. Murphy
author_facet Humraaz Samra
Katherin Leckie
Leni Moldovan
Kristen Wanczyk
Lava Timsina
Mithun Sinha
Imran Khan Mohammed
Ravi Mylvaganam
Anush Motaganahalli
Paul Territo
Ashley Gutwein
Raghunandan Motaganahalli
Michael P. Murphy
author_sort Humraaz Samra
collection DOAJ
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institution Directory Open Access Journal
issn 2666-3503
language English
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publishDate 2023-01-01
publisher Elsevier
record_format Article
series JVS - Vascular Science
spelling doaj.art-08e187218ffc478d81fd15b1a894ca402023-12-30T04:45:01ZengElsevierJVS - Vascular Science2666-35032023-01-014100159Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)Humraaz Samra0Katherin Leckie1Leni Moldovan2Kristen Wanczyk3Lava Timsina4Mithun Sinha5Imran Khan Mohammed6Ravi Mylvaganam7Anush Motaganahalli8Paul Territo9Ashley Gutwein10Raghunandan Motaganahalli11Michael P. Murphy12Indiana University, Indianapolis, INIndiana University, Indianapolis, INIUPUI AND VAMC, Indianapolis, INIUPUI AND VAMC, Indianapolis, INIndiana University, Indianapolis, INIndiana University, Indianapolis, INIndiana University, Indianapolis, INMassachusetts General Hospital, Boston, MAIndiana University, Indianapolis, INIndiana University, Indianapolis, INIndiana University, Indianapolis, INIndiana University, Indianapolis, INIndiana University, Indianapolis, INhttp://www.sciencedirect.com/science/article/pii/S2666350323000639
spellingShingle Humraaz Samra
Katherin Leckie
Leni Moldovan
Kristen Wanczyk
Lava Timsina
Mithun Sinha
Imran Khan Mohammed
Ravi Mylvaganam
Anush Motaganahalli
Paul Territo
Ashley Gutwein
Raghunandan Motaganahalli
Michael P. Murphy
Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)
JVS - Vascular Science
title Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)
title_full Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)
title_fullStr Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)
title_full_unstemmed Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)
title_short Allogeneic Mesenchymal Stromal Cells Significantly Increase Type 1 Regulatory T Cells, Decrease Effector Th17 Cells, and Decrease Aneurysm Volume in a Dose-dependent Fashion in Patients With Small Abdominal Aortic Aneurysms: Results of the Phase I Aneurysm Repression With Mesenchymal Stromal Cells (the Arrest Trial)
title_sort allogeneic mesenchymal stromal cells significantly increase type 1 regulatory t cells decrease effector th17 cells and decrease aneurysm volume in a dose dependent fashion in patients with small abdominal aortic aneurysms results of the phase i aneurysm repression with mesenchymal stromal cells the arrest trial
url http://www.sciencedirect.com/science/article/pii/S2666350323000639
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AT katherinleckie allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
AT lenimoldovan allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
AT kristenwanczyk allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
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AT mithunsinha allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
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AT anushmotaganahalli allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
AT paulterrito allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
AT ashleygutwein allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
AT raghunandanmotaganahalli allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst
AT michaelpmurphy allogeneicmesenchymalstromalcellssignificantlyincreasetype1regulatorytcellsdecreaseeffectorth17cellsanddecreaseaneurysmvolumeinadosedependentfashioninpatientswithsmallabdominalaorticaneurysmsresultsofthephaseianeurysmrepressionwithmesenchymalstromalcellst