Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells.

Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells.

Cytochrome P450 1B1 (CYP1B1) is a member of the cytochrome p450 family of enzymes that catalyze mono-oxygenase reactions. Although constitutive Cyp1b1 expression is limited in hepatocytes, its expression and function in liver sinusoidal endothelial cells (LSEC) remains unknown. Here we determined th...

Full description

Bibliographic Details
Main Authors:	Juliana Falero-Perez, Yong-Seok Song, Yun Zhao, Leandro Teixeira, Christine M Sorenson, Nader Sheibani
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2018-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC6205649?pdf=render

Similar Items

Retinal astrocytes transcriptome reveals Cyp1b1 regulates the expression of genes involved in cell adhesion and migration.
by: Juliana Falero-Perez, et al.
Published: (2020-01-01)

Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells
by: Yong-Seok Song, et al.
Published: (2023-01-01)

Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells.
by: Juliana Falero-Perez, et al.
Published: (2020-01-01)

Cytochrome P450 1B1 and primary congenital glaucoma
by: Yun Zhao, et al.
Published: (2015-01-01)

Liver sinusoidal endothelial cells: an antiviral "defendothelium".
by: Klenerman, P, et al.
Published: (2015)

Fingolimod (FTY720), a Sphinogosine-1-Phosphate Receptor Agonist, Mitigates Choroidal Endothelial Proangiogenic Properties and Choroidal Neovascularization
by: Christine M. Sorenson, et al.
Published: (2022-03-01)

Capillarized Liver Sinusoidal Endothelial Cells Undergo Partial Endothelial-Mesenchymal Transition to Actively Deposit Sinusoidal ECM in Liver Fibrosis
by: Bai Ruan, et al.
Published: (2021-07-01)

Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury
by: Sophia Papaioannou, et al.
Published: (2023-08-01)

Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization
by: Christine M. Sorenson, et al.
Published: (2021-04-01)

1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR‐mediated modulation of VEGF production and signaling of VEGF and PDGF receptors
by: Nasim Jamali, et al.
Published: (2019-07-01)

Expression of thrombospondin-1 modulates the angioinflammatory phenotype of choroidal endothelial cells.
by: Ping Fei, et al.
Published: (2014-01-01)

Liver sinusoidal endothelial cell expressed vascular cell adhesion molecule 1 promotes liver fibrosis
by: Qianqian Guo, et al.
Published: (2022-08-01)

Prominent Receptors of Liver Sinusoidal Endothelial Cells in Liver Homeostasis and Disease
by: Ekta Pandey, et al.
Published: (2020-07-01)

Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent
by: Ingelin Kyrrestad, et al.
Published: (2023-11-01)

Signature of gene expression profile of liver sinusoidal endothelial cells in nonalcoholic steatohepatitis
by: Yang Wang, et al.
Published: (2022-09-01)

Emerging Roles of Liver Sinusoidal Endothelial Cells in Nonalcoholic Steatohepatitis
by: Kunimaro Furuta, et al.
Published: (2020-11-01)

The liver sinusoidal endothelial cell damage in rats caused by heatstroke
by: Xingqin Zhang, et al.
Published: (2018-08-01)

The Scavenger Function of Liver Sinusoidal Endothelial Cells in Health and Disease
by: Sabin Bhandari, et al.
Published: (2021-10-01)

Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration
by: Xiaoying Luo, et al.
Published: (2017-10-01)

Cytochrome P450 1B1 Expression Regulates Intracellular Iron Levels and Oxidative Stress in the Retinal Endothelium
by: Yong-Seok Song, et al.
Published: (2023-01-01)

High glucose alters retinal astrocytes phenotype through increased production of inflammatory cytokines and oxidative stress.
by: Eui Seok Shin, et al.
Published: (2014-01-01)

Gut–Liver Axis: Liver Sinusoidal Endothelial Cells Function as the Hepatic Barrier in Colitis-Induced Liver Injury
by: Yang Wang, et al.
Published: (2021-07-01)

Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2
by: Christopher Holte, et al.
Published: (2023-11-01)

Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure
by: Hong Mao, et al.
Published: (2023-08-01)

Sulodexide attenuates liver fibrosis in mice by restoration of differentiated liver sinusoidal endothelial cell
by: Ru Huang, et al.
Published: (2023-04-01)

Gene Signatures Detect Damaged Liver Sinusoidal Endothelial Cells in Chronic Liver Diseases
by: Stefaan Verhulst, et al.
Published: (2021-10-01)

Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
by: Xiang Yu, et al.
Published: (2019-02-01)

Cytochrome P450 1B1: A Key Regulator of Ocular Iron Homeostasis and Oxidative Stress
by: Yong-Seok Song, et al.
Published: (2022-09-01)

Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6
by: Alexandre Balaphas, et al.
Published: (2020-05-01)

Diabetes and Retinal Vascular Dysfunction
by: Eui Seok Shin, et al.
Published: (2014-01-01)

Choroidal Mast Cells and Pathophysiology of Age-Related Macular Degeneration
by: Sara Malih, et al.
Published: (2023-12-01)

LSEC Fenestrae Are Preserved Despite Pro-inflammatory Phenotype of Liver Sinusoidal Endothelial Cells in Mice on High Fat Diet
by: Edyta Kus, et al.
Published: (2019-02-01)

Editorial: Ocular fibrosis: molecular and cellular mechanisms and treatment modalities
by: Christine M. Sorenson, et al.
Published: (2024-01-01)

Caffeine Inhibits Choroidal Neovascularization Through Mitigation of Inflammatory and Angiogenesis Activities
by: Christine M. Sorenson, et al.
Published: (2021-10-01)

The Crosstalk Between Liver Sinusoidal Endothelial Cells and Hepatic Microenvironment in NASH Related Liver Fibrosis
by: Wei Du, et al.
Published: (2022-06-01)

Liver Sinusoidal Endothelial Cells Escape Senescence by Loss of p19ARF.
by: Petra Koudelkova, et al.
Published: (2015-01-01)

Thrombospondin-1, BIM and CFH polymorphisms and response to anti-VEGF treatment in neovascular age- related macular degeneration patients
by: Christine M. Sorenson, et al.
Published: (2024-01-01)

Thrombospondin-1, BIM and CFH polymorphisms and response to anti-VEGF treatment in neovascular age- related macular degeneration patients.
by: Christine M Sorenson, et al.
Published: (2024-01-01)

Chemokine Transfer by Liver Sinusoidal Endothelial Cells Contributes to the Recruitment of CD4+ T Cells into the Murine Liver.
by: Katrin Neumann, et al.
Published: (2015-01-01)

Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma
by: Zhuo Yu, et al.
Published: (2022-01-01)