Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties
Linlin Zhong, Kyusik Yun Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea Abstract: Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functiona...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2015-08-01
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| Series: | International Journal of Nanomedicine |
| Online Access: | http://www.dovepress.com/graphene-oxide-modified-zno-particles-synthesis-characterization-and-a-peer-reviewed-article-IJN |
| _version_ | 1818695511083843584 |
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| author | Zhong LL Yun KS |
| author_facet | Zhong LL Yun KS |
| author_sort | Zhong LL |
| collection | DOAJ |
| description | Linlin Zhong, Kyusik Yun Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea Abstract: Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties. Keywords: graphene oxide, ZnO, characterization, antibacterial property |
| first_indexed | 2024-12-17T13:46:38Z |
| format | Article |
| id | doaj.art-08f05c4f9a604de5a87680524dff8316 |
| institution | Directory Open Access Journal |
| issn | 1178-2013 |
| language | English |
| last_indexed | 2024-12-17T13:46:38Z |
| publishDate | 2015-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nanomedicine |
| spelling | doaj.art-08f05c4f9a604de5a87680524dff83162022-12-21T21:46:09ZengDove Medical PressInternational Journal of Nanomedicine1178-20132015-08-012015Special Issue on diverse applications in Nano-Theranostics799223354Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial propertiesZhong LLYun KSLinlin Zhong, Kyusik Yun Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea Abstract: Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties. Keywords: graphene oxide, ZnO, characterization, antibacterial propertyhttp://www.dovepress.com/graphene-oxide-modified-zno-particles-synthesis-characterization-and-a-peer-reviewed-article-IJN |
| spellingShingle | Zhong LL Yun KS Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties International Journal of Nanomedicine |
| title | Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties |
| title_full | Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties |
| title_fullStr | Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties |
| title_full_unstemmed | Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties |
| title_short | Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties |
| title_sort | graphene oxide modified zno particles synthesis characterization and antibacterial properties |
| url | http://www.dovepress.com/graphene-oxide-modified-zno-particles-synthesis-characterization-and-a-peer-reviewed-article-IJN |
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