Fine particulate matter-induced lung inflammation is mediated by pyroptosis in mice

Fine particulate matter-induced lung inflammation is mediated by pyroptosis in mice

Background: Exposure to ambient air-borne fine particulate matter (PM2.5) increases respiratory morbidity and mortality. The mechanisms underlying PM2.5-induced adverse effects remain unclear. This study aimed to uncover the molecular mechanisms of PM2.5-induced lung toxicity using a mouse model. Me...

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Bibliographic Details
Main Authors: Juan Li, Zhen An, Jie Song, Jinge Du, Lin Zhang, Jing Jiang, Yanmei Ma, Chunzhi Wang, Jingfang Zhang, Weidong Wu
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PM2.5
Lung toxicity
Lung inflammation
NLRP3
Pyroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321004620

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