Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload
Abstract Background Two‐dimensional shear wave elastography (2D‐SWE) provides information on hepatic elastic modulus as shear wave velocity (SWV). Hypothesis/Objectives To assess SWV using 2D‐SWE in dogs with induced volume overload, investigate the relationship between this information and right at...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-05-01
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| Series: | Journal of Veterinary Internal Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jvim.16705 |
| _version_ | 1797816156828991488 |
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| author | Masahiro Tamura Hiroshi Ohta Tatsuyuki Osuga Mitsuyoshi Takiguchi |
| author_facet | Masahiro Tamura Hiroshi Ohta Tatsuyuki Osuga Mitsuyoshi Takiguchi |
| author_sort | Masahiro Tamura |
| collection | DOAJ |
| description | Abstract Background Two‐dimensional shear wave elastography (2D‐SWE) provides information on hepatic elastic modulus as shear wave velocity (SWV). Hypothesis/Objectives To assess SWV using 2D‐SWE in dogs with induced volume overload, investigate the relationship between this information and right atrial pressure (RAP) measured by invasive right heart catheterization, and also evaluate the difference in SWV before and after diuretic administration. Animals Six healthy beagles. Methods Prospective experimental study. Right heart catheterization and 2D‐SWE were performed in 6 anesthetized beagles at baseline and after the induction of volume overload. Volume overload was induced by IV hydroxyethyl starch 70/0.5 infusion (100 mL/kg/h). Furosemide (4‐6 mg/kg, IV) was administered, and the SWVs were measured. Results Shear wave velocity showed a significant gradual increase during acute volume overload compared to baseline. SWV was significantly positively correlated with RAP (P < .0001, ρ = 0.9729). The area under the curve of SWV to predict RAP at >10, >15, and >20 mm Hg was 0.9896 (95% confidence interval [95% CI], 0.9690‐1.000), 0.9907 (95% CI, 0.9701‐1.000), and 0.9722 (95% CI, 0.9280‐1.000), respectively. The SWV after diuretic use decreased significantly. Conclusions and Clinical Importance Two‐dimensional shear wave elastography might be useful for noninvasive and reliable estimation of RAP in dogs with acute volume overload and has potential as a quantitative biomarker for evaluating therapeutic response in dogs with right sided congestive heart failure. |
| first_indexed | 2024-03-13T08:33:31Z |
| format | Article |
| id | doaj.art-08f316bafe31449ea27c26cfa425562d |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-03-13T08:33:31Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-08f316bafe31449ea27c26cfa425562d2023-05-31T01:33:58ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762023-05-0137386687410.1111/jvim.16705Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overloadMasahiro Tamura0Hiroshi Ohta1Tatsuyuki Osuga2Mitsuyoshi Takiguchi3Laboratory of Companion Animal Internal Medicine, Department of Companion Animal Clinical Sciences, School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido JapanLaboratory of Companion Animal Internal Medicine, Department of Companion Animal Clinical Sciences, School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido JapanLaboratory of Veterinary Internal Medicine, Department of Veterinary Sciences University of Miyazaki Miyazaki Miyazaki JapanLaboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine Hokkaido University Sapporo Hokkaido JapanAbstract Background Two‐dimensional shear wave elastography (2D‐SWE) provides information on hepatic elastic modulus as shear wave velocity (SWV). Hypothesis/Objectives To assess SWV using 2D‐SWE in dogs with induced volume overload, investigate the relationship between this information and right atrial pressure (RAP) measured by invasive right heart catheterization, and also evaluate the difference in SWV before and after diuretic administration. Animals Six healthy beagles. Methods Prospective experimental study. Right heart catheterization and 2D‐SWE were performed in 6 anesthetized beagles at baseline and after the induction of volume overload. Volume overload was induced by IV hydroxyethyl starch 70/0.5 infusion (100 mL/kg/h). Furosemide (4‐6 mg/kg, IV) was administered, and the SWVs were measured. Results Shear wave velocity showed a significant gradual increase during acute volume overload compared to baseline. SWV was significantly positively correlated with RAP (P < .0001, ρ = 0.9729). The area under the curve of SWV to predict RAP at >10, >15, and >20 mm Hg was 0.9896 (95% confidence interval [95% CI], 0.9690‐1.000), 0.9907 (95% CI, 0.9701‐1.000), and 0.9722 (95% CI, 0.9280‐1.000), respectively. The SWV after diuretic use decreased significantly. Conclusions and Clinical Importance Two‐dimensional shear wave elastography might be useful for noninvasive and reliable estimation of RAP in dogs with acute volume overload and has potential as a quantitative biomarker for evaluating therapeutic response in dogs with right sided congestive heart failure.https://doi.org/10.1111/jvim.167052D‐SWEcanineright atrial pressureSWV |
| spellingShingle | Masahiro Tamura Hiroshi Ohta Tatsuyuki Osuga Mitsuyoshi Takiguchi Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload Journal of Veterinary Internal Medicine 2D‐SWE canine right atrial pressure SWV |
| title | Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload |
| title_full | Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload |
| title_fullStr | Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload |
| title_full_unstemmed | Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload |
| title_short | Effectiveness of 2‐dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload |
| title_sort | effectiveness of 2 dimensional shear wave elastography for noninvasive and reliable estimation of right atrial pressure in dogs with induced volume overload |
| topic | 2D‐SWE canine right atrial pressure SWV |
| url | https://doi.org/10.1111/jvim.16705 |
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