The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa
Abstract We use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data coll...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-94057-z |
| _version_ | 1818430419787317248 |
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| author | Aditi Kuber Anna Reuter Pascal Geldsetzer Natsayi Chimbindi Mosa Moshabela Frank Tanser Till Bärnighausen Sebastian Vollmer |
| author_facet | Aditi Kuber Anna Reuter Pascal Geldsetzer Natsayi Chimbindi Mosa Moshabela Frank Tanser Till Bärnighausen Sebastian Vollmer |
| author_sort | Aditi Kuber |
| collection | DOAJ |
| description | Abstract We use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data collected in 2010 in KwaZulu-Natal, South Africa, with clinical data on ART. We find that early ART eligibility significantly reduces systolic and diastolic blood pressure. We do not find any significant effects on BMI. The effect on blood pressure can be detected up to three years after becoming eligible for ART. |
| first_indexed | 2024-12-14T15:33:07Z |
| format | Article |
| id | doaj.art-08f3abab57694728b9633a8d6d02e2b1 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-14T15:33:07Z |
| publishDate | 2021-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-08f3abab57694728b9633a8d6d02e2b12022-12-21T22:55:48ZengNature PortfolioScientific Reports2045-23222021-07-011111910.1038/s41598-021-94057-zThe effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South AfricaAditi Kuber0Anna Reuter1Pascal Geldsetzer2Natsayi Chimbindi3Mosa Moshabela4Frank Tanser5Till Bärnighausen6Sebastian Vollmer7Department of Economics, University of GoettingenDepartment of Economics, University of GoettingenDivision of Primary Care and Population Health, Department of Medicine, Stanford UniversityAfrica Health Research InstituteAfrica Health Research InstituteAfrica Health Research InstituteAfrica Health Research InstituteDepartment of Economics, University of GoettingenAbstract We use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data collected in 2010 in KwaZulu-Natal, South Africa, with clinical data on ART. We find that early ART eligibility significantly reduces systolic and diastolic blood pressure. We do not find any significant effects on BMI. The effect on blood pressure can be detected up to three years after becoming eligible for ART.https://doi.org/10.1038/s41598-021-94057-z |
| spellingShingle | Aditi Kuber Anna Reuter Pascal Geldsetzer Natsayi Chimbindi Mosa Moshabela Frank Tanser Till Bärnighausen Sebastian Vollmer The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa Scientific Reports |
| title | The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa |
| title_full | The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa |
| title_fullStr | The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa |
| title_full_unstemmed | The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa |
| title_short | The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa |
| title_sort | effect of eligibility for antiretroviral therapy on body mass index and blood pressure in kwazulu natal south africa |
| url | https://doi.org/10.1038/s41598-021-94057-z |
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