Organocatalytic asymmetric allylic amination of Morita–Baylis–Hillman carbonates of isatins

Organocatalytic asymmetric allylic amination of Morita–Baylis–Hillman carbonates of isatins

The investigation of a Lewis base catalyzed asymmetric allylic amination of Morita–Baylis–Hillman carbonates derived from isatins afforded an electrophilic pathway to access multifunctional oxindoles bearing a C3-quaternary stereocenter, provided with good to excellent enantioselectivity (up to 94%...

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Hlavní autoři: Hang Zhang, Shan-Jun Zhang, Qing-Qing Zhou, Lin Dong, Ying-Chun Chen
Médium: Článek
Jazyk:English
Vydáno: Beilstein-Institut 2012-08-01
Edice:Beilstein Journal of Organic Chemistry
Témata:
allylic amination
asymmetric organocatalysis
Morita–Baylis–Hillman carbonates
2-oxindoles
quaternary chiral center
On-line přístup:https://doi.org/10.3762/bjoc.8.139

Internet

https://doi.org/10.3762/bjoc.8.139

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