Screening of Phosphodiesterase-5 Inhibitors and Their Analogs in Dietary Supplements by Liquid Chromatography–Hybrid Ion Trap–Time of Flight Mass Spectrometry

Screening of Phosphodiesterase-5 Inhibitors and Their Analogs in Dietary Supplements by Liquid Chromatography–Hybrid Ion Trap–Time of Flight Mass Spectrometry

An accurate and reliable method based on ion trap–time of flight mass spectrometry (IT–TOF MS) was developed for screening phosphodiesterase-5 inhibitors, including sildenafil, vardenafil, and tadalafil, and their analogs in dietary supplements. Various parameters affecting liquid chromatographic se...

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Bibliographic Details
Main Authors: Unyong Kim, Hyun-Deok Cho, Myung Hee Kang, Joon Hyuk Suh, Han Young Eom, Junghyun Kim, Sumin Seo, Gunwoo Kim, Hye Ryoung Koo, Nary Ha, Un Tak Song, Sang Beom Han
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
phosphodiesterase-5 inhibitors
analogs
dietary supplements
high-performance liquid chromatography
hybrid ion trap–time of flight mass spectrometry
Online Access:https://www.mdpi.com/1420-3049/25/12/2734

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