Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes
Electroporation-based cancer treatment techniques are currently after active investigations in the field of drug delivery, optimization of electrical parameters and elucidation of the exact mechanisms at a molecular level. The present study is designed to investigate the exact in vivo redistribution...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Bulgarian Academy of Sciences
2015-06-01
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| Series: | International Journal Bioautomation |
| Subjects: | |
| Online Access: | http://www.biomed.bas.bg/bioautomation/2015/vol_19.2/files/19.2_11.pdf |
| _version_ | 1818235367552188416 |
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| author | Biliana Nikolova Severina Atanasova Tsvetan Mudrov Iana Tsoneva Zhivko Zhelev Rumiana Bakalova Ichio Aoki |
| author_facet | Biliana Nikolova Severina Atanasova Tsvetan Mudrov Iana Tsoneva Zhivko Zhelev Rumiana Bakalova Ichio Aoki |
| author_sort | Biliana Nikolova |
| collection | DOAJ |
| description | Electroporation-based cancer treatment techniques are currently after active investigations in the field of drug delivery, optimization of electrical parameters and elucidation of the exact mechanisms at a molecular level. The present study is designed to investigate the exact in vivo redistribution and persistence of nanoparticles in the tumor tissue of colon-cancer grafted mice after electroporation with two different kinds of electrodes. The aim of the study is to avoid artifacts during electroporation due to accumulation of nanoparticles in the surrounding non-cancer tissues. The isolated electrodes are appropriate for the treatment of 3-dimensional tumors and have a large potential in this field. |
| first_indexed | 2024-12-12T11:52:51Z |
| format | Article |
| id | doaj.art-08f7fa01ed334acdbd064d2e55206338 |
| institution | Directory Open Access Journal |
| issn | 1314-1902 1314-2321 |
| language | English |
| last_indexed | 2024-12-12T11:52:51Z |
| publishDate | 2015-06-01 |
| publisher | Bulgarian Academy of Sciences |
| record_format | Article |
| series | International Journal Bioautomation |
| spelling | doaj.art-08f7fa01ed334acdbd064d2e552063382022-12-22T00:25:15ZengBulgarian Academy of SciencesInternational Journal Bioautomation1314-19021314-23212015-06-01192259266Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of ElectrodesBiliana Nikolova0Severina AtanasovaTsvetan MudrovIana TsonevaZhivko ZhelevRumiana BakalovaIchio AokiInstitute of Biophysics and Biomedical EngineeringBulgarian Academy of Sciences21 Acad. G. Bonchev Str., Sofia 1113, BulgariaElectroporation-based cancer treatment techniques are currently after active investigations in the field of drug delivery, optimization of electrical parameters and elucidation of the exact mechanisms at a molecular level. The present study is designed to investigate the exact in vivo redistribution and persistence of nanoparticles in the tumor tissue of colon-cancer grafted mice after electroporation with two different kinds of electrodes. The aim of the study is to avoid artifacts during electroporation due to accumulation of nanoparticles in the surrounding non-cancer tissues. The isolated electrodes are appropriate for the treatment of 3-dimensional tumors and have a large potential in this field.http://www.biomed.bas.bg/bioautomation/2015/vol_19.2/files/19.2_11.pdfElectroassisted drug deliveryin vivo imagingCancerNanoparticlesQuantum dots |
| spellingShingle | Biliana Nikolova Severina Atanasova Tsvetan Mudrov Iana Tsoneva Zhivko Zhelev Rumiana Bakalova Ichio Aoki Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes International Journal Bioautomation Electroassisted drug delivery in vivo imaging Cancer Nanoparticles Quantum dots |
| title | Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes |
| title_full | Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes |
| title_fullStr | Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes |
| title_full_unstemmed | Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes |
| title_short | Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes |
| title_sort | image guided electro assisted drug delivery comparison between two types of electrodes |
| topic | Electroassisted drug delivery in vivo imaging Cancer Nanoparticles Quantum dots |
| url | http://www.biomed.bas.bg/bioautomation/2015/vol_19.2/files/19.2_11.pdf |
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