High incidence of minor and micro breakpoints in Chronic Myeloid Leukaemia with additional cytogenetic abnormalities at diagnosis – the Western Australian series

High incidence of minor and micro breakpoints in Chronic Myeloid Leukaemia with additional cytogenetic abnormalities at diagnosis – the Western Australian series

Introduction and objective: Chronic Myeloid Leukaemia (CML) is defined by the presence of the Philadelphia chromosome, a balanced translocation between chromosomes 9 and 22 that results in the constitutively active tyrosine kinase, BCR-ABL1. Additional chromosomal abnormalities (ACAs) at diagnosis o...

Full description

Bibliographic Details
Main Authors: Emily Leung, Rebecca de Kraa, Alison Louw, Julian P. Cooney
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Leukemia Research Reports
Subjects:
Chronic Myeloid Leukaemia
Cytogenetics
Leukaemia
Tyrosine kinase inhibitors
Additional chromosomal abnormalities
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048922000565

Internet

http://www.sciencedirect.com/science/article/pii/S2213048922000565

Similar Items