Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging
Intracranial atherosclerosis is one of the leading causes of ischemic stroke and occurs more commonly in patients of Asian, African or Hispanic origin than in Caucasians. Although the histopathology of intracranial atherosclerotic disease resembles extracranial atherosclerosis, there are some notabl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Korean Stroke Society
2017-09-01
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| Series: | Journal of Stroke |
| Subjects: | |
| Online Access: | http://www.j-stroke.org/upload/pdf/jos-2016-01956.pdf |
| _version_ | 1818930077325328384 |
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| author | Wen-jie Yang Ka-sing Wong Xiang-yan Chen |
| author_facet | Wen-jie Yang Ka-sing Wong Xiang-yan Chen |
| author_sort | Wen-jie Yang |
| collection | DOAJ |
| description | Intracranial atherosclerosis is one of the leading causes of ischemic stroke and occurs more commonly in patients of Asian, African or Hispanic origin than in Caucasians. Although the histopathology of intracranial atherosclerotic disease resembles extracranial atherosclerosis, there are some notable differences in the onset and severity of atherosclerosis. Current understanding of intracranial atherosclerotic disease has been advanced by the high-resolution magnetic resonance imaging (HRMRI), a novel emerging imaging technique that can directly visualize the vessel wall pathology. However, the pathological validation of HRMRI signal characteristics remains a key step to depict the plaque components and vulnerability in intracranial atherosclerotic lesions. The purpose of this review is to describe the histological features of intracranial atherosclerosis and to state current evidences regarding the validation of MR vessel wall imaging with histopathology. |
| first_indexed | 2024-12-20T03:54:58Z |
| format | Article |
| id | doaj.art-08fb16ac776c494ba7b45bf577ee6f38 |
| institution | Directory Open Access Journal |
| issn | 2287-6391 2287-6405 |
| language | English |
| last_indexed | 2024-12-20T03:54:58Z |
| publishDate | 2017-09-01 |
| publisher | Korean Stroke Society |
| record_format | Article |
| series | Journal of Stroke |
| spelling | doaj.art-08fb16ac776c494ba7b45bf577ee6f382022-12-21T19:54:22ZengKorean Stroke SocietyJournal of Stroke2287-63912287-64052017-09-0119324926010.5853/jos.2016.01956192Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance ImagingWen-jie Yang0Ka-sing Wong1Xiang-yan Chen Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Sha Tin, Hong Kong Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Sha Tin, Hong KongIntracranial atherosclerosis is one of the leading causes of ischemic stroke and occurs more commonly in patients of Asian, African or Hispanic origin than in Caucasians. Although the histopathology of intracranial atherosclerotic disease resembles extracranial atherosclerosis, there are some notable differences in the onset and severity of atherosclerosis. Current understanding of intracranial atherosclerotic disease has been advanced by the high-resolution magnetic resonance imaging (HRMRI), a novel emerging imaging technique that can directly visualize the vessel wall pathology. However, the pathological validation of HRMRI signal characteristics remains a key step to depict the plaque components and vulnerability in intracranial atherosclerotic lesions. The purpose of this review is to describe the histological features of intracranial atherosclerosis and to state current evidences regarding the validation of MR vessel wall imaging with histopathology.http://www.j-stroke.org/upload/pdf/jos-2016-01956.pdfintracranial atherosclerosisautopsyhistologymagnetic resonance imaging |
| spellingShingle | Wen-jie Yang Ka-sing Wong Xiang-yan Chen Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging Journal of Stroke intracranial atherosclerosis autopsy histology magnetic resonance imaging |
| title | Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging |
| title_full | Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging |
| title_fullStr | Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging |
| title_full_unstemmed | Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging |
| title_short | Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging |
| title_sort | intracranial atherosclerosis from microscopy to high resolution magnetic resonance imaging |
| topic | intracranial atherosclerosis autopsy histology magnetic resonance imaging |
| url | http://www.j-stroke.org/upload/pdf/jos-2016-01956.pdf |
| work_keys_str_mv | AT wenjieyang intracranialatherosclerosisfrommicroscopytohighresolutionmagneticresonanceimaging AT kasingwong intracranialatherosclerosisfrommicroscopytohighresolutionmagneticresonanceimaging AT xiangyanchen intracranialatherosclerosisfrommicroscopytohighresolutionmagneticresonanceimaging |