| Summary: | The use of plants as medicine has been trusted by the community since time immemorial. Sanrego (Lunasia amara Blanco.) is one plant that has been believed to be an aphrodisiac. Sanrego is a wild plant found in the forests of Sulawesi, Java, Borneo, Maluku, Philippines, Papua New Guinea and Australia, and belongs to the Rutaceae Family. Sanrego has several properties such as treating stomach pain, anti-inflammatory, anti-cancer, snake bites and increasing sexual aggressiveness. This is because sanrego has bioactive ingredients as pharmacological. Sanrego extract contains secondary metabolites or bioactive compounds that include flavanoids, tannins, alakloids, steroids and saponins. Given the large variety of bioactive compounds in a sanrego plant, it is necessary to pay attention to extraction techniques in filtering these compounds. Some environmentally friendly extraction methods that can be used include maceration extraction methods, soxhlet, reflux, ultasonic, microwave, and enzyme assistance. This review discusses and describes the various extraction techniques used to obtain plant bioactive compounds. These extraction techniques include conventional extraction techniques and non-conventional extraction techniques. This review analyzes the advantages and disadvantages of this extraction technique. This review covers the application of extraction methods to sanrego plants.
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