Central pressure should be used in clinical practice

The original purpose for recording brachial blood pressure (BP) more than 100 years ago was to estimate central (aortic) BP. While high brachial BP is an important cardiovascular risk factor, it is clear that major differences in central systolic BP (SBP; e.g. >30 mmHg) can occur among people wit...

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Main Author: James E. Sharman
Format: Article
Language:English
Published: BMC 2014-12-01
Series:Artery Research
Subjects:
Online Access:https://www.atlantis-press.com/article/125925205/view
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author James E. Sharman
author_facet James E. Sharman
author_sort James E. Sharman
collection DOAJ
description The original purpose for recording brachial blood pressure (BP) more than 100 years ago was to estimate central (aortic) BP. While high brachial BP is an important cardiovascular risk factor, it is clear that major differences in central systolic BP (SBP; e.g. >30 mmHg) can occur among people with similar brachial SBP. It is also proven that central SBP responses to antihypertensive therapy can differ substantially from brachial SBP responses, such that true treatment effects cannot be gauged from conventional brachial BP. Importantly, assessment of central BP results in: 1) improved predictive accuracy of future cardiovascular events beyond brachial BP and other cardiovascular risk factors; 2) superior diagnostic accuracy over brachial BP and; 3) different patient management than usual care guided by brachial BP. Collectively, the above illustrates that central BP is a better cardiovascular risk biomarker than brachial BP. As with all medical advances there are areas of research need and international consensus is required on issues such as standardization of techniques. However, central BP can now be accurately estimated (with appropriate waveform calibration) using brachial cuff methods in an approach that is familiar to clinicians, acceptable to patients and amenable to widespread use. In other words, this modern BP technique can finally satisfy the original purpose for measuring central aortic BP as intended more than 100 years ago. Although the tipping point towards routine use is yet to be reached, the body of evidence continues to favour the view that central BP should be used in clinical practice.
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spelling doaj.art-0909917f83224eab8a3766cb4602b2c62022-12-22T02:56:47ZengBMCArtery Research1876-44012014-12-01910.1016/j.artres.2014.11.001Central pressure should be used in clinical practiceJames E. SharmanThe original purpose for recording brachial blood pressure (BP) more than 100 years ago was to estimate central (aortic) BP. While high brachial BP is an important cardiovascular risk factor, it is clear that major differences in central systolic BP (SBP; e.g. >30 mmHg) can occur among people with similar brachial SBP. It is also proven that central SBP responses to antihypertensive therapy can differ substantially from brachial SBP responses, such that true treatment effects cannot be gauged from conventional brachial BP. Importantly, assessment of central BP results in: 1) improved predictive accuracy of future cardiovascular events beyond brachial BP and other cardiovascular risk factors; 2) superior diagnostic accuracy over brachial BP and; 3) different patient management than usual care guided by brachial BP. Collectively, the above illustrates that central BP is a better cardiovascular risk biomarker than brachial BP. As with all medical advances there are areas of research need and international consensus is required on issues such as standardization of techniques. However, central BP can now be accurately estimated (with appropriate waveform calibration) using brachial cuff methods in an approach that is familiar to clinicians, acceptable to patients and amenable to widespread use. In other words, this modern BP technique can finally satisfy the original purpose for measuring central aortic BP as intended more than 100 years ago. Although the tipping point towards routine use is yet to be reached, the body of evidence continues to favour the view that central BP should be used in clinical practice.https://www.atlantis-press.com/article/125925205/viewHaemodynamicAortaBlood vesselsBrachial artery
spellingShingle James E. Sharman
Central pressure should be used in clinical practice
Artery Research
Haemodynamic
Aorta
Blood vessels
Brachial artery
title Central pressure should be used in clinical practice
title_full Central pressure should be used in clinical practice
title_fullStr Central pressure should be used in clinical practice
title_full_unstemmed Central pressure should be used in clinical practice
title_short Central pressure should be used in clinical practice
title_sort central pressure should be used in clinical practice
topic Haemodynamic
Aorta
Blood vessels
Brachial artery
url https://www.atlantis-press.com/article/125925205/view
work_keys_str_mv AT jamesesharman centralpressureshouldbeusedinclinicalpractice