Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum

A splenic lesion often represents a diagnostic challenge due to relative scarcity and the broad differential diagnosis. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is usually encountered only incidentally. Although benign, patients with SANT often receive splenectomy, due to i...

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Main Authors: Sander Van den Eede, Nick Van de Voorde, Filip Vanhoenacker, Bart Op de Beeck
Format: Article
Language:English
Published: Ubiquity Press 2022-04-01
Series:Journal of the Belgian Society of Radiology
Subjects:
Online Access:https://www.jbsr.be/articles/2689
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author Sander Van den Eede
Nick Van de Voorde
Filip Vanhoenacker
Bart Op de Beeck
author_facet Sander Van den Eede
Nick Van de Voorde
Filip Vanhoenacker
Bart Op de Beeck
author_sort Sander Van den Eede
collection DOAJ
description A splenic lesion often represents a diagnostic challenge due to relative scarcity and the broad differential diagnosis. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is usually encountered only incidentally. Although benign, patients with SANT often receive splenectomy, due to its rarity, diagnostic uncertainty and sometimes intimidating imaging morphology and size. Imaging features on computed tomography, magnetic resonance and positron emission tomography have a high diagnostic value for SANT and help differentiate this entity from other splenic lesions. When the imaging parameters are matched with core needle biopsy tissue analysis, further watchful waiting can be recommended in order to avoid splenectomy.
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spelling doaj.art-090ad4c8ee3a460cbb0b056e09d46d762022-12-22T02:53:01ZengUbiquity PressJournal of the Belgian Society of Radiology2514-82812022-04-01106110.5334/jbsr.26891448Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic ConundrumSander Van den Eede0Nick Van de Voorde1Filip Vanhoenacker2Bart Op de Beeck3University of AntwerpAntwerp University Hospital and Antwerp University, EdegemAZ Sint-Maarten, Mechelen; AZ Sint-Maarten and University (Hospital) Antwerp/GhentAntwerp University Hospital and Antwerp University, EdegemA splenic lesion often represents a diagnostic challenge due to relative scarcity and the broad differential diagnosis. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is usually encountered only incidentally. Although benign, patients with SANT often receive splenectomy, due to its rarity, diagnostic uncertainty and sometimes intimidating imaging morphology and size. Imaging features on computed tomography, magnetic resonance and positron emission tomography have a high diagnostic value for SANT and help differentiate this entity from other splenic lesions. When the imaging parameters are matched with core needle biopsy tissue analysis, further watchful waiting can be recommended in order to avoid splenectomy.https://www.jbsr.be/articles/2689sclerosing angiomatoid nodular transformationsplenic lesionsmultimodality imagingimage guided biopsysplenectomy
spellingShingle Sander Van den Eede
Nick Van de Voorde
Filip Vanhoenacker
Bart Op de Beeck
Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum
Journal of the Belgian Society of Radiology
sclerosing angiomatoid nodular transformation
splenic lesions
multimodality imaging
image guided biopsy
splenectomy
title Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum
title_full Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum
title_fullStr Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum
title_full_unstemmed Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum
title_short Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum
title_sort sclerosing angiomatoid nodular transformation of the spleen a diagnostic conundrum
topic sclerosing angiomatoid nodular transformation
splenic lesions
multimodality imaging
image guided biopsy
splenectomy
url https://www.jbsr.be/articles/2689
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AT nickvandevoorde sclerosingangiomatoidnodulartransformationofthespleenadiagnosticconundrum
AT filipvanhoenacker sclerosingangiomatoidnodulartransformationofthespleenadiagnosticconundrum
AT bartopdebeeck sclerosingangiomatoidnodulartransformationofthespleenadiagnosticconundrum