Macromolecular crowding and decellularization method increase the growth factor binding potential of cell-secreted extracellular matrices

Macromolecular crowding and decellularization method increase the growth factor binding potential of cell-secreted extracellular matrices

Recombinant growth factors are used in tissue engineering to stimulate cell proliferation, migration, and differentiation. Conventional methods of growth factor delivery for therapeutic applications employ large amounts of these bioactive cues. Effective, localized growth factor release is essential...

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Bibliographic Details
Main Authors: Shierly W. Fok, Robert C. H. Gresham, Weston Ryan, Benjamin Osipov, Chelsea Bahney, J. Kent Leach
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
macromolecular crowding
decellularization
BMP-2
bone
growth factors
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1091157/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1091157/full

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