Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review
Abstract Alcohol drinking is a popular activity among adolescents in many countries, largely due to its pleasant, relaxing effects. As a major concern, ethanol consumption put the drinkers at risk of nutrients' deficiency due to the disordered eating, anorexia, and malabsorption of nutrients. M...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-09-01
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| Series: | Food Science & Nutrition |
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| Online Access: | https://doi.org/10.1002/fsn3.3520 |
| _version_ | 1797688574811832320 |
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| author | Masoumeh Moslemi Behrooz Jannat Maryam Mahmoudzadeh Mehran Ghasemlou Abdol‐Samad Abedi |
| author_facet | Masoumeh Moslemi Behrooz Jannat Maryam Mahmoudzadeh Mehran Ghasemlou Abdol‐Samad Abedi |
| author_sort | Masoumeh Moslemi |
| collection | DOAJ |
| description | Abstract Alcohol drinking is a popular activity among adolescents in many countries, largely due to its pleasant, relaxing effects. As a major concern, ethanol consumption put the drinkers at risk of nutrients' deficiency due to the disordered eating, anorexia, and malabsorption of nutrients. Moreover, alcohol drinking may lead to the development of hangover symptoms including diarrhea, thirsty, fatigue, and oxidative stress. A broad range of functional food components with antioxidant and/or anti‐inflammatory properties including pectin, aloe vera polysaccharides, chito‐oligosaccharides, and other herbal components have been explored due to their detoxification effects against ethanol. The underlying anti‐hangover mechanisms include reducing the intestinal absorption of ethanol or its metabolites, increasing the activity of ethanol metabolizing enzymes, development of fatty acid β‐oxidation in mitochondria, inhibition of inflammatory response, blocking the target receptors of ethanol in the body, and possession of antioxidant activity under the oxidative stress developed by ethanol consumption. Therefore, the development of bioactive food‐based therapeutic formula can assist clinicians and also drinkers in the alleviation of alcohol side effects. |
| first_indexed | 2024-03-12T01:32:51Z |
| format | Article |
| id | doaj.art-090ced01df5149d78904196c4a0a822a |
| institution | Directory Open Access Journal |
| issn | 2048-7177 |
| language | English |
| last_indexed | 2024-03-12T01:32:51Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Food Science & Nutrition |
| spelling | doaj.art-090ced01df5149d78904196c4a0a822a2023-09-11T13:25:12ZengWileyFood Science & Nutrition2048-71772023-09-011195028504010.1002/fsn3.3520Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A reviewMasoumeh Moslemi0Behrooz Jannat1Maryam Mahmoudzadeh2Mehran Ghasemlou3Abdol‐Samad Abedi4Halal Research Center of IRI Ministry of Health and Medical Education Tehran IranHalal Research Center of IRI Ministry of Health and Medical Education Tehran IranNutrition Research Center and Department of Food Science and Technology, Faculty of Nutrition and Food Science Tabriz University of Medical Sciences Tabriz IranSchool of Science STEM College, RMIT University Melbourne Victoria AustraliaDepartment of Research Deputy, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology Shahid Beheshti University of Medical Sciences Tehran IranAbstract Alcohol drinking is a popular activity among adolescents in many countries, largely due to its pleasant, relaxing effects. As a major concern, ethanol consumption put the drinkers at risk of nutrients' deficiency due to the disordered eating, anorexia, and malabsorption of nutrients. Moreover, alcohol drinking may lead to the development of hangover symptoms including diarrhea, thirsty, fatigue, and oxidative stress. A broad range of functional food components with antioxidant and/or anti‐inflammatory properties including pectin, aloe vera polysaccharides, chito‐oligosaccharides, and other herbal components have been explored due to their detoxification effects against ethanol. The underlying anti‐hangover mechanisms include reducing the intestinal absorption of ethanol or its metabolites, increasing the activity of ethanol metabolizing enzymes, development of fatty acid β‐oxidation in mitochondria, inhibition of inflammatory response, blocking the target receptors of ethanol in the body, and possession of antioxidant activity under the oxidative stress developed by ethanol consumption. Therefore, the development of bioactive food‐based therapeutic formula can assist clinicians and also drinkers in the alleviation of alcohol side effects.https://doi.org/10.1002/fsn3.3520anti‐hangover agentsbioactive food compoundsdetoxificationethanolfood supplementationnutrient deficiency |
| spellingShingle | Masoumeh Moslemi Behrooz Jannat Maryam Mahmoudzadeh Mehran Ghasemlou Abdol‐Samad Abedi Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review Food Science & Nutrition anti‐hangover agents bioactive food compounds detoxification ethanol food supplementation nutrient deficiency |
| title | Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review |
| title_full | Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review |
| title_fullStr | Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review |
| title_full_unstemmed | Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review |
| title_short | Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review |
| title_sort | detoxification activity of bioactive food compounds against ethanol induced injuries and hangover symptoms a review |
| topic | anti‐hangover agents bioactive food compounds detoxification ethanol food supplementation nutrient deficiency |
| url | https://doi.org/10.1002/fsn3.3520 |
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