Malaria research challenges in low prevalence settings

<p>Abstract</p> <p>The prevalence of malaria has reduced significantly in some areas over the past decade. These reductions have made local elimination possible and the research agenda has shifted to this new priority. However, there are critical issues that arise when studying mal...

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Main Authors: Stresman Gillian, Kobayashi Tamaki, Kamanga Aniset, Thuma Philip E, Mharakurwa Sungano, Moss William J, Shiff Clive
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Malaria Journal
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author Stresman Gillian
Kobayashi Tamaki
Kamanga Aniset
Thuma Philip E
Mharakurwa Sungano
Moss William J
Shiff Clive
author_facet Stresman Gillian
Kobayashi Tamaki
Kamanga Aniset
Thuma Philip E
Mharakurwa Sungano
Moss William J
Shiff Clive
author_sort Stresman Gillian
collection DOAJ
description <p>Abstract</p> <p>The prevalence of malaria has reduced significantly in some areas over the past decade. These reductions have made local elimination possible and the research agenda has shifted to this new priority. However, there are critical issues that arise when studying malaria in low transmission settings, particularly identifying asymptomatic infections, accurate detection of individuals with microparasitaemic infections, and achieving a sufficient sample size to have an adequately powered study. These challenges could adversely impact the study of malaria elimination if they remain unanswered.</p>
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spelling doaj.art-090d97ff84a8420cae5225e74f02bf272022-12-22T03:27:58ZengBMCMalaria Journal1475-28752012-10-0111135310.1186/1475-2875-11-353Malaria research challenges in low prevalence settingsStresman GillianKobayashi TamakiKamanga AnisetThuma Philip EMharakurwa SunganoMoss William JShiff Clive<p>Abstract</p> <p>The prevalence of malaria has reduced significantly in some areas over the past decade. These reductions have made local elimination possible and the research agenda has shifted to this new priority. However, there are critical issues that arise when studying malaria in low transmission settings, particularly identifying asymptomatic infections, accurate detection of individuals with microparasitaemic infections, and achieving a sufficient sample size to have an adequately powered study. These challenges could adversely impact the study of malaria elimination if they remain unanswered.</p>
spellingShingle Stresman Gillian
Kobayashi Tamaki
Kamanga Aniset
Thuma Philip E
Mharakurwa Sungano
Moss William J
Shiff Clive
Malaria research challenges in low prevalence settings
Malaria Journal
title Malaria research challenges in low prevalence settings
title_full Malaria research challenges in low prevalence settings
title_fullStr Malaria research challenges in low prevalence settings
title_full_unstemmed Malaria research challenges in low prevalence settings
title_short Malaria research challenges in low prevalence settings
title_sort malaria research challenges in low prevalence settings
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AT kamangaaniset malariaresearchchallengesinlowprevalencesettings
AT thumaphilipe malariaresearchchallengesinlowprevalencesettings
AT mharakurwasungano malariaresearchchallengesinlowprevalencesettings
AT mosswilliamj malariaresearchchallengesinlowprevalencesettings
AT shiffclive malariaresearchchallengesinlowprevalencesettings