The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19
Nowadays, Bacillus Calmette-Guérin (BCG) is the most commonly used vaccine worldwide, used typically for tuberculosis but also in non-muscle invasive bladder cancer management. Basing on previously confirmed antiviral features of BCG and first statistic data reports, BCG usage in COVID-19 preventio...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2022-10-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | https://apcz.umk.pl/JEHS/article/view/40380 |
| _version_ | 1817979721778987008 |
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| author | Jakub Krzysztof Gałązka |
| author_facet | Jakub Krzysztof Gałązka |
| author_sort | Jakub Krzysztof Gałązka |
| collection | DOAJ |
| description |
Nowadays, Bacillus Calmette-Guérin (BCG) is the most commonly used vaccine worldwide, used typically for tuberculosis but also in non-muscle invasive bladder cancer management. Basing on previously confirmed antiviral features of BCG and first statistic data reports, BCG usage in COVID-19 prevention was claimed and its potential molecular mechanism was searched. In scientific literature there was 10 publications proving several possible mechanism of BCG interaction with SARS-CoV-2 infection immune response. The most often was cross-reactivity between various BCG and SARS-CoV-2 antigens, including those crucial for their clinical effects. In most cases, those antigens linking was shown according to bioinformatical research. According to this research, the potential role of BCG in COVID-19 management should be considered as significant, at least until the clinical trials conducted nowadays will be over.
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| first_indexed | 2024-04-13T22:46:08Z |
| format | Article |
| id | doaj.art-090fc76be7fc4db4849cf9a41595a634 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-13T22:46:08Z |
| publishDate | 2022-10-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-090fc76be7fc4db4849cf9a41595a6342022-12-22T02:26:23ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062022-10-01121010.12775/JEHS.2022.12.10.016The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19Jakub Krzysztof Gałązka0Students’ Scientific Association at Chair and Department of Clinical Immunology, Medical University of Lublin, Chodźki 4A, 20-093 Lublin, Poland Nowadays, Bacillus Calmette-Guérin (BCG) is the most commonly used vaccine worldwide, used typically for tuberculosis but also in non-muscle invasive bladder cancer management. Basing on previously confirmed antiviral features of BCG and first statistic data reports, BCG usage in COVID-19 prevention was claimed and its potential molecular mechanism was searched. In scientific literature there was 10 publications proving several possible mechanism of BCG interaction with SARS-CoV-2 infection immune response. The most often was cross-reactivity between various BCG and SARS-CoV-2 antigens, including those crucial for their clinical effects. In most cases, those antigens linking was shown according to bioinformatical research. According to this research, the potential role of BCG in COVID-19 management should be considered as significant, at least until the clinical trials conducted nowadays will be over. https://apcz.umk.pl/JEHS/article/view/40380BCGBacillus Calmette-GuérinvaccineCOVID-19 |
| spellingShingle | Jakub Krzysztof Gałązka The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19 Journal of Education, Health and Sport BCG Bacillus Calmette-Guérin vaccine COVID-19 |
| title | The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19 |
| title_full | The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19 |
| title_fullStr | The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19 |
| title_full_unstemmed | The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19 |
| title_short | The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19 |
| title_sort | impact of bacillus calmette guerin bcg vaccination on the course of covid 19 |
| topic | BCG Bacillus Calmette-Guérin vaccine COVID-19 |
| url | https://apcz.umk.pl/JEHS/article/view/40380 |
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