Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosa
Background: Scropholaria striata Boiss. From Scropholariaceae (Teshnehdari in folklore of Ilam Province, Iran) is used for treatment of infectious disease of urinary tract especially in females. Objective: In this research for finding of the most effective part of the plant, crude extract of the aer...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Institue of Medicinal Plants, ACECR
2014-12-01
|
| Series: | Journal of Medicinal Plants |
| Subjects: | |
| Online Access: | http://jmp.ir/article-1-873-en.html |
| _version_ | 1819107359814844416 |
|---|---|
| author | H Ayobi H Jamalifar F Pour Mohammadi S Goodarzi MR Fazeli F Attar A Hadjiakhoondi N Yassa |
| author_facet | H Ayobi H Jamalifar F Pour Mohammadi S Goodarzi MR Fazeli F Attar A Hadjiakhoondi N Yassa |
| author_sort | H Ayobi |
| collection | DOAJ |
| description | Background: Scropholaria striata Boiss. From Scropholariaceae (Teshnehdari in folklore of Ilam Province, Iran) is used for treatment of infectious disease of urinary tract especially in females. Objective: In this research for finding of the most effective part of the plant, crude extract of the aerial parts of S. striata and its different fractions was investigated on the 50 resistant strains of Psudomonas aeroginosa. Methods: Crude extract of the plant and its various fractions (chloroform, methanol and water) were prepared. Bacterial strains were collected from 3 hospitals and 50 resistant strains were isolated from the culture medium containing various antibiotics. Efficacy of the all fractions was investigated on these resistant bacterial strains. Result: Water and methanol fractions of the plant were showed more antibacterial activity on 50 resistant strains of P. aeroginosa than crude extract (p=0.0001 and p=0.001 respectively) and water fraction was showed stronger effect than methanol fraction (p=0.001). Chloroform fraction of the plant had no antibacterial activity on this resistant strain. Conclusion: The results of this study showed that the water extract of Scropholaria striata can be used as a remedy for the treatment of the infections caused by Psudomonas aeroginosa. |
| first_indexed | 2024-12-22T02:52:47Z |
| format | Article |
| id | doaj.art-0917ae66904a4b7e919ed1c096b1af82 |
| institution | Directory Open Access Journal |
| issn | 2717-204X 2717-2058 |
| language | English |
| last_indexed | 2024-12-22T02:52:47Z |
| publishDate | 2014-12-01 |
| publisher | Institue of Medicinal Plants, ACECR |
| record_format | Article |
| series | Journal of Medicinal Plants |
| spelling | doaj.art-0917ae66904a4b7e919ed1c096b1af822022-12-21T18:41:20ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582014-12-0113527380Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosaH Ayobi0H Jamalifar1F Pour Mohammadi2S Goodarzi3MR Fazeli4F Attar5A Hadjiakhoondi6N Yassa7 1- Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran 2- Department of Food and Drug Control, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 1- Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran 1- Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran 2- Department of Food and Drug Control, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 3- Department of Plant Sciences, School of Biology, College of Science, University of Tehran, Tehran, Iran 1- Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran 1- Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran Background: Scropholaria striata Boiss. From Scropholariaceae (Teshnehdari in folklore of Ilam Province, Iran) is used for treatment of infectious disease of urinary tract especially in females. Objective: In this research for finding of the most effective part of the plant, crude extract of the aerial parts of S. striata and its different fractions was investigated on the 50 resistant strains of Psudomonas aeroginosa. Methods: Crude extract of the plant and its various fractions (chloroform, methanol and water) were prepared. Bacterial strains were collected from 3 hospitals and 50 resistant strains were isolated from the culture medium containing various antibiotics. Efficacy of the all fractions was investigated on these resistant bacterial strains. Result: Water and methanol fractions of the plant were showed more antibacterial activity on 50 resistant strains of P. aeroginosa than crude extract (p=0.0001 and p=0.001 respectively) and water fraction was showed stronger effect than methanol fraction (p=0.001). Chloroform fraction of the plant had no antibacterial activity on this resistant strain. Conclusion: The results of this study showed that the water extract of Scropholaria striata can be used as a remedy for the treatment of the infections caused by Psudomonas aeroginosa.http://jmp.ir/article-1-873-en.htmlpsudomonas aeroginosascropholaria striataantibacterial effectsscropholariaceae |
| spellingShingle | H Ayobi H Jamalifar F Pour Mohammadi S Goodarzi MR Fazeli F Attar A Hadjiakhoondi N Yassa Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosa Journal of Medicinal Plants psudomonas aeroginosa scropholaria striata antibacterial effects scropholariaceae |
| title | Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosa |
| title_full | Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosa |
| title_fullStr | Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosa |
| title_full_unstemmed | Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosa |
| title_short | Antibacterial Effects of Scrophularia striata Extract on Pseudomonas aeruginosa |
| title_sort | antibacterial effects of scrophularia striata extract on pseudomonas aeruginosa |
| topic | psudomonas aeroginosa scropholaria striata antibacterial effects scropholariaceae |
| url | http://jmp.ir/article-1-873-en.html |
| work_keys_str_mv | AT hayobi antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa AT hjamalifar antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa AT fpourmohammadi antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa AT sgoodarzi antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa AT mrfazeli antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa AT fattar antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa AT ahadjiakhoondi antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa AT nyassa antibacterialeffectsofscrophulariastriataextractonpseudomonasaeruginosa |