Quantification of Salmonella enterica serovar Typhimurium population dynamics in murine infection using a highly diverse barcoded library

Quantification of Salmonella enterica serovar Typhimurium population dynamics in murine infection using a highly diverse barcoded library

Murine models are often used to study the pathogenicity and dissemination of the enteric pathogen Salmonella enterica serovar Typhimurium. Here, we quantified S. Typhimurium population dynamics in mice using the STAMPR analytic pipeline and a highly diverse S. Typhimurium barcoded library containing...

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Bibliographic Details
Main Authors: Julia A Hotinger, Ian W Campbell, Karthik Hullahalli, Akina Osaki, Matthew K Waldor
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
Subjects:
Salmonella enterica serovar Typhimurium
infectious disease
microbial population dynamics
barcode lineage tracing
population bottleneck
disseminated bacterial infection
Online Access:https://elifesciences.org/articles/101388

Internet

https://elifesciences.org/articles/101388

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