New Piperazine Derivatives of 6-Acetyl-7-hydroxy-4-methylcoumarin as 5-HT<sub>1A</sub> Receptor Agents

A series of 15 new derivatives of 6-acetyl-7-hydroxy-4-methylcoumarin containing a piperazine group were designed with the help of computational methods and were synthesized to study their affinity for the serotonin 5-HT<sub>1A</sub> and 5-HT<sub>2A</sub> receptors. Among the...

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Bibliographic Details
Main Authors: Kinga Ostrowska, Anna Leśniak, Weronika Gryczka, Łukasz Dobrzycki, Magdalena Bujalska-Zadrożny, Bartosz Trzaskowski
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/3/2779