Comprehensive comparative analysis of histopathology and gene expression in subchondral bone between kashin-beck disease and primary osteoarthritis

Comprehensive comparative analysis of histopathology and gene expression in subchondral bone between kashin-beck disease and primary osteoarthritis

Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy that exhibits some similar characteristics to osteoarthritis (OA) but with different etiologies and pathogeneses. In addition to cartilage damage, microstructural changes of bone were observed in KBD. This study aimed to comparat...

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Bibliographic Details
Main Authors: Lei Yang, Jingwen Sun, Ying Zhang, Xiong Guo, Guanghui Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
kashin-beck disease
osteoarthritis
subchondral bone
histopathology
RNA sequencing
microRNA array
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.942326/full

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