Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma

Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma

BackgroundThe mechanism of copper-induced cellular death was newly discovered and termed cuproptosis. Inducing cuproptosis in cancer cells is well anticipated for its curative potential in treating tumor diseases. However, ferredoxin 1 (FDX1), the core regulatory gene in cuproptosis, is rarely studi...

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Bibliographic Details
Main Authors: Jiahao Xu, Zhengang Hu, Hui Cao, Hao Zhang, Peng Luo, Jian Zhang, Xiaoyan Wang, Quan Cheng, Jingbo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
cuproptosis
FDX1
pan-cancer
immunology
KIRC
notch
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.981764/full

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