Novel Ligands Targeting α4β1 Integrin: Therapeutic Applications and Perspectives

Novel Ligands Targeting α4β1 Integrin: Therapeutic Applications and Perspectives

Among the other members of the adhesion molecules' family, α4β1 integrin, a heterodimeric receptor, plays a crucial role in inflammatory diseases, cancer development, metastasis and stem cell mobilization or retention. In many cases, its function in pathogenesis is not yet completely understood...

Full description

Bibliographic Details
Main Authors: Monica Baiula, Santi Spampinato, Luca Gentilucci, Alessandra Tolomelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Chemistry
Subjects:
α4β1 integrin
agonist
antagonist
small molecules
inflammatory disorders
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00489/full

Similar Items

Similar Items