Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed Rats
Objective: Noise as a natural teratogenic factor affects the body systems including the reproductive organ to reduce the fertility rate and fetus health. Honey and vitamin E as natural antioxidants protects the sperm released from the reproductive system. This study was conducted to exam...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Aras Part Medical International Press
2015-04-01
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| Series: | Crescent Journal of Medical and Biological Sciences |
| Subjects: | |
| Online Access: | http://cjmb.org/PDF/CJMB-2-64.pdf |
| _version_ | 1818541963510546432 |
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| author | Rajabzadeh Asghar Sagha Mohsen Gholami Mohammad Reza Hemmati Reza |
| author_facet | Rajabzadeh Asghar Sagha Mohsen Gholami Mohammad Reza Hemmati Reza |
| author_sort | Rajabzadeh Asghar |
| collection | DOAJ |
| description | Objective: Noise as a natural teratogenic factor affects the body systems including the reproductive organ
to reduce the fertility rate and fetus health. Honey and vitamin E as natural antioxidants protects the
sperm released from the reproductive system. This study was conducted to examine the efficacy of honey
and vitamin E on fertilization capacity in noise-exposed rats by assessing plasma sexual hormones levels
i.e., follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone, altered in relation
with noise stress.
Materials and Methods: This study was targeted the 24 male rats that randomly were divided into four
equal groups including one control group (unexposed to noise stress) and three experimental groups
pre-induced with noise stress for 50 days and then divided as: no treated, honey and vitamin E treated
groups, respectively. Then, the blood samples of experimental and control groups were taken, and the
serum level of the sexual hormones was analyzed. Finally, to investigate the fertility capacity of rats, the
male rats of all groups were coupled with the female ones.
Results: Our results showed that FSH and LH level in noise stressed male rats raised, and the testosterone
secretion decreased compared to the control group. Moreover, noise stress injury could reduce weight and
the survival rate of the fetus. However, the honey and vitamin E improved the testosterone concentration,
declined the plasma FSH and LH level in noise - exposed rats and enhanced the fertility rate.
Conclusion: These findings may also spell out a natural curative approach rather than pharmaceutical
drugs to optimize of neuroendocrine gonadal axis and testicular integrity induced by pathogenesis stress,
i.e., noise and enhance the male fertility capacity. |
| first_indexed | 2024-12-11T22:15:59Z |
| format | Article |
| id | doaj.art-091d697c918b4dbf97fb39af42fb5adf |
| institution | Directory Open Access Journal |
| issn | 2148-9696 |
| language | English |
| last_indexed | 2024-12-11T22:15:59Z |
| publishDate | 2015-04-01 |
| publisher | Aras Part Medical International Press |
| record_format | Article |
| series | Crescent Journal of Medical and Biological Sciences |
| spelling | doaj.art-091d697c918b4dbf97fb39af42fb5adf2022-12-22T00:48:35ZengAras Part Medical International PressCrescent Journal of Medical and Biological Sciences2148-96962015-04-01226468CJMB_20150712111101Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed RatsRajabzadeh Asghar0Sagha Mohsen1Gholami Mohammad Reza2Hemmati Reza3Department of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranResearch Laboratory for Embryology and Stem Cells AND Department of Anatomical Sciences and Pathology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, IranDepartment of Anatomical Sciences, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, IranDepartment of Anatomical Sciences, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, IranObjective: Noise as a natural teratogenic factor affects the body systems including the reproductive organ to reduce the fertility rate and fetus health. Honey and vitamin E as natural antioxidants protects the sperm released from the reproductive system. This study was conducted to examine the efficacy of honey and vitamin E on fertilization capacity in noise-exposed rats by assessing plasma sexual hormones levels i.e., follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone, altered in relation with noise stress. Materials and Methods: This study was targeted the 24 male rats that randomly were divided into four equal groups including one control group (unexposed to noise stress) and three experimental groups pre-induced with noise stress for 50 days and then divided as: no treated, honey and vitamin E treated groups, respectively. Then, the blood samples of experimental and control groups were taken, and the serum level of the sexual hormones was analyzed. Finally, to investigate the fertility capacity of rats, the male rats of all groups were coupled with the female ones. Results: Our results showed that FSH and LH level in noise stressed male rats raised, and the testosterone secretion decreased compared to the control group. Moreover, noise stress injury could reduce weight and the survival rate of the fetus. However, the honey and vitamin E improved the testosterone concentration, declined the plasma FSH and LH level in noise - exposed rats and enhanced the fertility rate. Conclusion: These findings may also spell out a natural curative approach rather than pharmaceutical drugs to optimize of neuroendocrine gonadal axis and testicular integrity induced by pathogenesis stress, i.e., noise and enhance the male fertility capacity.http://cjmb.org/PDF/CJMB-2-64.pdfGonadal HormonesHoneyNoiseVitamin E |
| spellingShingle | Rajabzadeh Asghar Sagha Mohsen Gholami Mohammad Reza Hemmati Reza Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed Rats Crescent Journal of Medical and Biological Sciences Gonadal Hormones Honey Noise Vitamin E |
| title | Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed Rats |
| title_full | Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed Rats |
| title_fullStr | Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed Rats |
| title_full_unstemmed | Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed Rats |
| title_short | Honey and Vitamin E Restore the Plasma Level of Gonadal Hormones and Improve the Fertilization Capacity in Noise-Stressed Rats |
| title_sort | honey and vitamin e restore the plasma level of gonadal hormones and improve the fertilization capacity in noise stressed rats |
| topic | Gonadal Hormones Honey Noise Vitamin E |
| url | http://cjmb.org/PDF/CJMB-2-64.pdf |
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