Ovarian Cancer Stem Cells: Role in Metastasis and Opportunity for Therapeutic Targeting

Ovarian Cancer Stem Cells: Role in Metastasis and Opportunity for Therapeutic Targeting

Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage. Cancer stem cells (CSCs) that exist within the bulk tumor survive first-line chemotherapy and contribute to resistant disease with metastasis. Understanding the key features of CSC biology provides valuable opportuniti...

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Bibliographic Details
Main Authors: Xingyue Zong, Kenneth P. Nephew
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
cancer stem cells
metastasis
ovarian cancer
Online Access:https://www.mdpi.com/2072-6694/11/7/934

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