Iron accumulation induced by hepcidin1 knockout accelerates the progression of aging osteoporosis

Iron accumulation induced by hepcidin1 knockout accelerates the progression of aging osteoporosis

Abstract Objective Iron accumulation is associated with osteoporosis. This study aims to explore the effect of chronic iron accumulation induced by hepcidin1 deficiency on aging osteoporosis. Methods Iron accumulation in hepcidin1 knockout aging mice was assessed by atomic absorption spectroscopy an...

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Bibliographic Details
Main Authors: Lu-lin Liu, Zhong-rui Liu, Lu-jun Cao, Jun Wang, San-ming Huang, Shui-gen Hu, Yi-zhong Yang, Dong-sheng Li, Wei-wei Cao, Qing-bao Zeng, Sheng Huang, Qiong Wu, Jian-hua Xiao, Wu-yang Liu, Yao-sheng Xiao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Iron
Hepcidin
Osteoporosis
Aged mice
Online Access:https://doi.org/10.1186/s13018-024-04535-z

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