NFIL3/Tim3 axis regulates effector Th1 inflammation in COPD mice

NFIL3/Tim3 axis regulates effector Th1 inflammation in COPD mice

BackgroundIFN-γ+CD4+ cells (type 1 helper T cells, Th1) represent a critical component of the inflammatory environment in the lungs of chronic obstructive pulmonary disease (COPD). Identifying influencing factors related to COPD-associated Th1 cells will enhance our understanding of the inflammatory...

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Bibliographic Details
Main Authors: Junyi Ke, Shu Huang, Zhixiong He, Siyu Lei, Shiya Lin, Yinying Li, Qiuming Li, Hui Huang, Hongchun Huang, Huajiao Qin, Minchao Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
Tim3
Th1
COPD
NFIL3
flow cytometry
single-cell sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1482213/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1482213/full

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