Incidence and risk of QTc interval prolongation among cancer patients treated with vandetanib: a systematic review and meta-analysis.

Vandetanib is a multikinase inhibitor that is under assessment for the treatment of various cancers. QTc interval prolongation is one of the major adverse effects of this drug, but the reported incidence varies substantially among clinical trials. We performed a systematic review and meta-analysis t...

Full description

Bibliographic Details
Main Authors: Jiajie Zang, Shunquan Wu, Lei Tang, Xudong Xu, Jie Bai, Caicui Ding, Yue Chang, Long Yue, Enming Kang, Jia He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281826?pdf=render