Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature
We report the rare case of a primary malignant melanoma of the urethra. An 89-year-old African American woman who was referred to our urology clinic for intermittent gross hematuria and a palpable vaginal mass of two months duration. Cystoscopy revealed a 3 cm mass in the distal urethra and urethral...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442021002758 |
| _version_ | 1818723844244897792 |
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| author | Mariela Martinez Srinath Kotamarti Ariel Schulman Unni Mooppan Jen Wang |
| author_facet | Mariela Martinez Srinath Kotamarti Ariel Schulman Unni Mooppan Jen Wang |
| author_sort | Mariela Martinez |
| collection | DOAJ |
| description | We report the rare case of a primary malignant melanoma of the urethra. An 89-year-old African American woman who was referred to our urology clinic for intermittent gross hematuria and a palpable vaginal mass of two months duration. Cystoscopy revealed a 3 cm mass in the distal urethra and urethral meatus that was surgically resected by wide local excision. The histopathologic diagnosis was primary malignant melanoma of the urethra. The patient was subsequently treated with adjuvant EBRT and immunotherapy with nivolumab and ipilimumab. Post-treatment PET-CT showed good response to treatment and patient remained in remission at eight month follow up. |
| first_indexed | 2024-12-17T21:16:58Z |
| format | Article |
| id | doaj.art-092b22a2f9104384801c426ed118feab |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-12-17T21:16:58Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-092b22a2f9104384801c426ed118feab2022-12-21T21:32:19ZengElsevierUrology Case Reports2214-44202022-01-0140101835Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literatureMariela Martinez0Srinath Kotamarti1Ariel Schulman2Unni Mooppan3Jen Wang4Division of Urology, Maimonides Research Center, Brooklyn, NY, USA; Corresponding author. 465 46th St Apt 6, Brooklyn, NY, 11220, USA.Division of Urology, Maimonides Research Center, Brooklyn, NY, USADivision of Urology, Maimonides Research Center, Brooklyn, NY, USADivision of Urology, Brookdale Hospital Medical Center, Brooklyn, NY, USADivision of Hematology/Oncology, Brookdale Hospital Medical Center, Brooklyn, NY, USAWe report the rare case of a primary malignant melanoma of the urethra. An 89-year-old African American woman who was referred to our urology clinic for intermittent gross hematuria and a palpable vaginal mass of two months duration. Cystoscopy revealed a 3 cm mass in the distal urethra and urethral meatus that was surgically resected by wide local excision. The histopathologic diagnosis was primary malignant melanoma of the urethra. The patient was subsequently treated with adjuvant EBRT and immunotherapy with nivolumab and ipilimumab. Post-treatment PET-CT showed good response to treatment and patient remained in remission at eight month follow up.http://www.sciencedirect.com/science/article/pii/S2214442021002758Malignant melanomaImmunotherapyOncologyUrethra |
| spellingShingle | Mariela Martinez Srinath Kotamarti Ariel Schulman Unni Mooppan Jen Wang Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature Urology Case Reports Malignant melanoma Immunotherapy Oncology Urethra |
| title | Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature |
| title_full | Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature |
| title_fullStr | Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature |
| title_full_unstemmed | Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature |
| title_short | Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature |
| title_sort | primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy case report and review of literature |
| topic | Malignant melanoma Immunotherapy Oncology Urethra |
| url | http://www.sciencedirect.com/science/article/pii/S2214442021002758 |
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