STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDE
Stability of microparticles of alprazolam in natural conditions was studied by the method of "accelerated aging". It was established that microparticles of alprazolam were not exposed to disruption and their appearance was not altered during the research. Expiration dates of alprazolam mic...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute
2015-09-01
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| Series: | Фармация и фармакология (Пятигорск) |
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| Online Access: | https://www.pharmpharm.ru/jour/article/view/43 |
| _version_ | 1797874726877528064 |
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| author | A. I. Medvetskiy L. I. Scherbakova V. A. Kompantsev L. P. Gokghayeva T. M. Vasina |
| author_facet | A. I. Medvetskiy L. I. Scherbakova V. A. Kompantsev L. P. Gokghayeva T. M. Vasina |
| author_sort | A. I. Medvetskiy |
| collection | DOAJ |
| description | Stability of microparticles of alprazolam in natural conditions was studied by the method of "accelerated aging". It was established that microparticles of alprazolam were not exposed to disruption and their appearance was not altered during the research. Expiration dates of alprazolam microparticles determination was calculated using the formula of J.H. van't Hoff. The expiration date made 2 years. |
| first_indexed | 2024-04-10T01:36:34Z |
| format | Article |
| id | doaj.art-092e948e4c1c454f8bddd936d19b4f57 |
| institution | Directory Open Access Journal |
| issn | 2307-9266 2413-2241 |
| language | Russian |
| last_indexed | 2024-04-10T01:36:34Z |
| publishDate | 2015-09-01 |
| publisher | Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute |
| record_format | Article |
| series | Фармация и фармакология (Пятигорск) |
| spelling | doaj.art-092e948e4c1c454f8bddd936d19b4f572023-03-13T09:18:09ZrusVolgograd State Medical University, Pyatigorsk Medical and Pharmaceutical InstituteФармация и фармакология (Пятигорск)2307-92662413-22412015-09-0124(5)637010.19163/2307-9266-2014-2-4(5)-63-7043STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDEA. I. Medvetskiy0L. I. Scherbakova1V. A. Kompantsev2L. P. Gokghayeva3T. M. Vasina4Пятигорский медико-фармацевтический институт – филиал ГБОУ ВПО ВолгГМУ Минздрава России, г. ПятигорскПятигорский медико-фармацевтический институт – филиал ГБОУ ВПО ВолгГМУ Минздрава России, г. ПятигорскПятигорский медико-фармацевтический институт – филиал ГБОУ ВПО ВолгГМУ Минздрава России, г. ПятигорскПятигорский медико-фармацевтический институт – филиал ГБОУ ВПО ВолгГМУ Минздрава России, г. ПятигорскПятигорский медико-фармацевтический институт – филиал ГБОУ ВПО ВолгГМУ Минздрава России, г. ПятигорскStability of microparticles of alprazolam in natural conditions was studied by the method of "accelerated aging". It was established that microparticles of alprazolam were not exposed to disruption and their appearance was not altered during the research. Expiration dates of alprazolam microparticles determination was calculated using the formula of J.H. van't Hoff. The expiration date made 2 years.https://www.pharmpharm.ru/jour/article/view/43алпразоламмикрочастицыполи-dl-лактид-ко-гликолидтревожные расстройства |
| spellingShingle | A. I. Medvetskiy L. I. Scherbakova V. A. Kompantsev L. P. Gokghayeva T. M. Vasina STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDE Фармация и фармакология (Пятигорск) алпразолам микрочастицы поли-d l-лактид-ко-гликолид тревожные расстройства |
| title | STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDE |
| title_full | STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDE |
| title_fullStr | STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDE |
| title_full_unstemmed | STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDE |
| title_short | STUDY OF STABILITY AND EXPIRATION DATE ESTABLISHIMENT OF MICROPARTICLES OF ALPRAZOLAM ON THE BASIS OF POLY-D,L-LACTIDE-CO-GLYCOLIDE |
| title_sort | study of stability and expiration date establishiment of microparticles of alprazolam on the basis of poly d l lactide co glycolide |
| topic | алпразолам микрочастицы поли-d l-лактид-ко-гликолид тревожные расстройства |
| url | https://www.pharmpharm.ru/jour/article/view/43 |
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