Autologous Platelet- and Extracellular Vesicle-Rich Plasma Is an Effective Treatment Modality for Chronic Postoperative Temporal Bone Cavity Inflammation: Randomized Controlled Clinical Trial

Autologous Platelet- and Extracellular Vesicle-Rich Plasma Is an Effective Treatment Modality for Chronic Postoperative Temporal Bone Cavity Inflammation: Randomized Controlled Clinical Trial

PurposeTo determine the efficacy of autologous platelet- and extracellular vesicle-rich plasma (PVRP) to treat chronic postoperative temporal bone cavity inflammation (CPTBCI) after exhausting surgical and standard conservative therapies.Materials and MethodsPatients were randomly allocated to treat...

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Bibliographic Details
Main Authors: Domen Vozel, Darja Božič, Marko Jeran, Zala Jan, Manca Pajnič, Ljubiša Pađen, Nejc Steiner, Veronika Kralj-Iglič, Saba Battelino
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
regenerative medicine
mastoidectomy
cholesteatoma
theranostic nanomedicine
quality of life
temporal bone
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.677541/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2021.677541/full

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