Astilbin antagonizes developmental cardiotoxicity after cadmium exposure in chicken embryos by inhibiting endoplasmic reticulum stress and maintaining calcium homeostasis

Astilbin antagonizes developmental cardiotoxicity after cadmium exposure in chicken embryos by inhibiting endoplasmic reticulum stress and maintaining calcium homeostasis

Cadmium (Cd) is a dangerous heavy metal with high toxicity that is known to impair development. Astilbin (ASB) is a protective flavonoid compound. We aimed to explore whether ASB can antagonize the myocardial developmental toxicity of Cd exposure. Cd (2 µg) and/or ASB (0.002 µg) were injected into e...

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Bibliographic Details
Main Authors: Yue Zhu, Haoyue Guan, Xingxi Zhu, Jingzeng Cai, Xing Jiao, Jianhua Shan, Yangyang Li, Qiong Wu, Ziwei Zhang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
Flavonoids
Myocardium
Development
Chicken Embryos
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323013519

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