Torsin Mediates Primary Envelopment of Large Ribonucleoprotein Granules at the Nuclear Envelope

Torsin Mediates Primary Envelopment of Large Ribonucleoprotein Granules at the Nuclear Envelope

A previously unrecognized mechanism through which large ribonucleoprotein (megaRNP) granules exit the nucleus is by budding through the nuclear envelope (NE). This mechanism is akin to the nuclear egress of herpes-type viruses and is essential for proper synapse development. However, the molecular m...

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Bibliographic Details
Main Authors: Vahbiz Jokhi, James Ashley, John Nunnari, Akiko Noma, Naoto Ito, Noriko Wakabayashi-Ito, Melissa J. Moore, Vivian Budnik
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001228

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