Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysis
Abstract Background Research on obesity in women of reproductive age is heterogeneous in gestational age and body mass index (BMI) classification and focused mostly on pregnancy-related rather than medical comorbidities. We studied the prevalences of pre-pregnancy BMI, chronic maternal and obstetric...
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Journal of Anesthesia, Analgesia and Critical Care |
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| Online Access: | https://doi.org/10.1186/s44158-023-00105-7 |
| _version_ | 1797789471496732672 |
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| author | Roi Gat Eran Hadar Sharon Orbach-Zinger Sharon Einav |
| author_facet | Roi Gat Eran Hadar Sharon Orbach-Zinger Sharon Einav |
| author_sort | Roi Gat |
| collection | DOAJ |
| description | Abstract Background Research on obesity in women of reproductive age is heterogeneous in gestational age and body mass index (BMI) classification and focused mostly on pregnancy-related rather than medical comorbidities. We studied the prevalences of pre-pregnancy BMI, chronic maternal and obstetric comorbidities, and delivery outcomes. Methods Retrospective analysis of real-time data collected during deliveries in a single tertiary medical center. Pre-pregnancy BMI was classified into seven groups (kg/m2): underweight (BMI < 18.5), normal weight 1 (18.5 ≤ BMI < 22.5), normal weight 2 (22.5 ≤ BMI < 25.0), overweight 1 (25.0 ≤ BMI < 27.5), overweight 2 (27.5 ≤ BMI < 30.0), obese (30.0 ≤ BMI < 35.0), and morbidly obese (BMI ≥ 35.0). Data were collected on maternal demographics, chronic medical and obstetric comorbidities, and delivery outcomes. Results Included were 13,726 women aged 18–50 years, with a gestational age of 240/7–416/7 weeks. Pre-pregnancy weights were 61.4% normal, 19.8% overweight, 7.6% obese, and 3.3% morbidly obese. Smoking was more prevalent among morbidly obese than among normal weight women. Obese and morbidly obese women were older and had more diabetes mellitus, hypertension, preeclampsia/eclampsia, and prior cesarean deliveries than normal weight parturients. Obese and morbidly obese women were also less likely to have a non-spontaneous conception, enter labor spontaneously (observed in the full study population and in a subgroup of term parturients), and were more likely to undergo cesarean rather than vaginal delivery. Subgroup analysis of primiparous women yielded similar results. Conclusions We identified a potential association between pre-pregnancy obesity and morbid obesity and higher rates of obstetric comorbidities, less natural conception and spontaneous labor, and more cesarean deliveries and adverse delivery outcomes. It remains to be seen if these findings remain after adjustment and whether they are related to obesity, treatment, or both. |
| first_indexed | 2024-03-13T01:51:08Z |
| format | Article |
| id | doaj.art-093705d4b70f49d5a8f5cf77e85f15e7 |
| institution | Directory Open Access Journal |
| issn | 2731-3786 |
| language | English |
| last_indexed | 2024-03-13T01:51:08Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Anesthesia, Analgesia and Critical Care |
| spelling | doaj.art-093705d4b70f49d5a8f5cf77e85f15e72023-07-02T11:29:33ZengBMCJournal of Anesthesia, Analgesia and Critical Care2731-37862023-06-013111510.1186/s44158-023-00105-7Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysisRoi Gat0Eran Hadar1Sharon Orbach-Zinger2Sharon Einav3Department of Internal Medicine, Tel Aviv Sourasky Medical CenterSackler Faculty of Medicine, Tel Aviv UniversitySackler Faculty of Medicine, Tel Aviv UniversityGeneral Intensive Care Unit, Shaare Zedek Medical CenterAbstract Background Research on obesity in women of reproductive age is heterogeneous in gestational age and body mass index (BMI) classification and focused mostly on pregnancy-related rather than medical comorbidities. We studied the prevalences of pre-pregnancy BMI, chronic maternal and obstetric comorbidities, and delivery outcomes. Methods Retrospective analysis of real-time data collected during deliveries in a single tertiary medical center. Pre-pregnancy BMI was classified into seven groups (kg/m2): underweight (BMI < 18.5), normal weight 1 (18.5 ≤ BMI < 22.5), normal weight 2 (22.5 ≤ BMI < 25.0), overweight 1 (25.0 ≤ BMI < 27.5), overweight 2 (27.5 ≤ BMI < 30.0), obese (30.0 ≤ BMI < 35.0), and morbidly obese (BMI ≥ 35.0). Data were collected on maternal demographics, chronic medical and obstetric comorbidities, and delivery outcomes. Results Included were 13,726 women aged 18–50 years, with a gestational age of 240/7–416/7 weeks. Pre-pregnancy weights were 61.4% normal, 19.8% overweight, 7.6% obese, and 3.3% morbidly obese. Smoking was more prevalent among morbidly obese than among normal weight women. Obese and morbidly obese women were older and had more diabetes mellitus, hypertension, preeclampsia/eclampsia, and prior cesarean deliveries than normal weight parturients. Obese and morbidly obese women were also less likely to have a non-spontaneous conception, enter labor spontaneously (observed in the full study population and in a subgroup of term parturients), and were more likely to undergo cesarean rather than vaginal delivery. Subgroup analysis of primiparous women yielded similar results. Conclusions We identified a potential association between pre-pregnancy obesity and morbid obesity and higher rates of obstetric comorbidities, less natural conception and spontaneous labor, and more cesarean deliveries and adverse delivery outcomes. It remains to be seen if these findings remain after adjustment and whether they are related to obesity, treatment, or both.https://doi.org/10.1186/s44158-023-00105-7PregnancyOverweightObesityBMIMedicalObstetric |
| spellingShingle | Roi Gat Eran Hadar Sharon Orbach-Zinger Sharon Einav Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysis Journal of Anesthesia, Analgesia and Critical Care Pregnancy Overweight Obesity BMI Medical Obstetric |
| title | Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysis |
| title_full | Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysis |
| title_fullStr | Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysis |
| title_full_unstemmed | Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysis |
| title_short | Medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients: a retrospective analysis |
| title_sort | medical and obstetric comorbidities and delivery outcomes in overweight and obese parturients a retrospective analysis |
| topic | Pregnancy Overweight Obesity BMI Medical Obstetric |
| url | https://doi.org/10.1186/s44158-023-00105-7 |
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