Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation
Abstract palmitoylation, a reversible post-translational modification, is initiated by the DHHC family of palmitoyltransferases and reversed by several acyl protein thioesterases. However, the role and mechanisms for protein palmitoylation in renal fibrosis have not been elucidated. Here we show pro...
Main Authors: | Mengru Gu, Hanlu Jiang, Mengzhu Tan, Long Yu, Ning Xu, Ying Li, Han Wu, Qing Hou, Chunsun Dai |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-42476-z |
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