Formulation development, optimization and characterization of Pemigatinib-loaded supersaturable self-nanoemulsifying drug delivery systems

Formulation development, optimization and characterization of Pemigatinib-loaded supersaturable self-nanoemulsifying drug delivery systems

Abstract Background Pemigatinib is a small molecule tyrosine kinase inhibitor of fibroblast growth factor receptor inhibitors. The oral bioavailability of Pemigatinib is constricted due to its limited solubility at physiological pH. It is essential to develop a novel formulation of Pemigatinib to im...

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Bibliographic Details
Main Authors:	Muthadi Radhika Reddy, Kumar Shiva Gubbiyappa
Format:	Article
Language:	English
Published:	SpringerOpen 2022-11-01
Series:	Future Journal of Pharmaceutical Sciences
Subjects:	Pemigatinib Precipitation inhibitor Optimization Simplex-lattice design Self-emulsification
Online Access:	https://doi.org/10.1186/s43094-022-00434-4

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