TLR4 signalling protects Sertoli cells from cell stress via reprogramming inflammasome and autophagy pathways in MAPK1/ERK2 dependent way

TLR4 signalling protects Sertoli cells from cell stress via reprogramming inflammasome and autophagy pathways in MAPK1/ERK2 dependent way

AbstractSertoli cells constitutively maintain the spermatogonial stem cell niche and blood-testis barrier via impenetrable tight junctions under hormonal, growth factor and cytokine control. Immature Sertoli cell proliferation and survival benefit from FSH, NF-κB, and IL-1α-dependent signalling effe...

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Bibliographic Details
Main Authors: Elina Avramska, Ilka Tsvetkova, Krassimira Todorova, Soren Hayrabedyan
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Sertoli cells
TLR4
mapk1/erk2
NF-kappaB
voltage-gated potassium channels
Online Access:https://www.tandfonline.com/doi/10.1080/13102818.2023.2268749

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