Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability

Abstract We examined the impact of a history of coronary artery disease (CAD) or cerebrovascular disease (CVD) and physical activity habits on functional disability among community-dwelling Japanese adults. This population-based retrospective cohort study included 10,661 people aged 39–98 years in J...

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Main Authors: Remi Kodera, Kazuya Fujihara, Tetsuya Koyama, Haruka Shiozaki, Yurie Mutsuma, Noriko Yagyuda, Mariko Hatta, Kahori Tsuruoka, Yasunada Takeda, Atsushi Araki, Hirohito Sone
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47913-z
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author Remi Kodera
Kazuya Fujihara
Tetsuya Koyama
Haruka Shiozaki
Yurie Mutsuma
Noriko Yagyuda
Mariko Hatta
Kahori Tsuruoka
Yasunada Takeda
Atsushi Araki
Hirohito Sone
author_facet Remi Kodera
Kazuya Fujihara
Tetsuya Koyama
Haruka Shiozaki
Yurie Mutsuma
Noriko Yagyuda
Mariko Hatta
Kahori Tsuruoka
Yasunada Takeda
Atsushi Araki
Hirohito Sone
author_sort Remi Kodera
collection DOAJ
description Abstract We examined the impact of a history of coronary artery disease (CAD) or cerebrovascular disease (CVD) and physical activity habits on functional disability among community-dwelling Japanese adults. This population-based retrospective cohort study included 10,661 people aged 39–98 years in Japan (5054, men). Median follow-up was 3.7 years. During the study period, 209 functional disabilities occurred in the overall study population. In multivariable analysis, a history of CVD (hazard ratio [HR] 1.57 [95% CI: 1.00–2.45]) and no physical activity habit (HR 1.74 [1.27–2.39]) presented increased risks for functional disability. HRs for functional disability among patients with a CVD history with and without a physical activity habit were 1.68 (0.75–3.74) and 2.65 (1.49–4.71), respectively, compared with individuals without a history of CVD with a physical activity habit. Similar results were observed for CAD. We found no significant difference in the incidence of functional disability between the group with a history of CAD or CVD and physical activity habits and the group with no history of CAD or CVD and without physical activity habits. Physical activity habits had a favorable influence on avoiding functional disability regardless of a history of CAD or CVD. Future prospective studies are needed to clarify these associations.
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spelling doaj.art-09492a7d470a4e2983736c7ce584e7f52023-12-03T12:23:03ZengNature PortfolioScientific Reports2045-23222023-11-011311810.1038/s41598-023-47913-zImpact of a history of cardiovascular disease and physical activity habits on the incidence of functional disabilityRemi Kodera0Kazuya Fujihara1Tetsuya Koyama2Haruka Shiozaki3Yurie Mutsuma4Noriko Yagyuda5Mariko Hatta6Kahori Tsuruoka7Yasunada Takeda8Atsushi Araki9Hirohito Sone10Department of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Internal Medicine, Niigata University Faculty of MedicineDepartment of Diabetes, Metabolism, and Endocrinology, Tokyo Metropolitan Institute for Geriatrics and GerontologyDepartment of Internal Medicine, Niigata University Faculty of MedicineAbstract We examined the impact of a history of coronary artery disease (CAD) or cerebrovascular disease (CVD) and physical activity habits on functional disability among community-dwelling Japanese adults. This population-based retrospective cohort study included 10,661 people aged 39–98 years in Japan (5054, men). Median follow-up was 3.7 years. During the study period, 209 functional disabilities occurred in the overall study population. In multivariable analysis, a history of CVD (hazard ratio [HR] 1.57 [95% CI: 1.00–2.45]) and no physical activity habit (HR 1.74 [1.27–2.39]) presented increased risks for functional disability. HRs for functional disability among patients with a CVD history with and without a physical activity habit were 1.68 (0.75–3.74) and 2.65 (1.49–4.71), respectively, compared with individuals without a history of CVD with a physical activity habit. Similar results were observed for CAD. We found no significant difference in the incidence of functional disability between the group with a history of CAD or CVD and physical activity habits and the group with no history of CAD or CVD and without physical activity habits. Physical activity habits had a favorable influence on avoiding functional disability regardless of a history of CAD or CVD. Future prospective studies are needed to clarify these associations.https://doi.org/10.1038/s41598-023-47913-z
spellingShingle Remi Kodera
Kazuya Fujihara
Tetsuya Koyama
Haruka Shiozaki
Yurie Mutsuma
Noriko Yagyuda
Mariko Hatta
Kahori Tsuruoka
Yasunada Takeda
Atsushi Araki
Hirohito Sone
Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability
Scientific Reports
title Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability
title_full Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability
title_fullStr Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability
title_full_unstemmed Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability
title_short Impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability
title_sort impact of a history of cardiovascular disease and physical activity habits on the incidence of functional disability
url https://doi.org/10.1038/s41598-023-47913-z
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