Tumor Suppressive Role of MUC6 in Wilms Tumor via Autophagy-Dependent β-Catenin Degradation

Tumor Suppressive Role of MUC6 in Wilms Tumor via Autophagy-Dependent β-Catenin Degradation

Wilms tumor is the most common renal malignancy in children. Known gene mutations account for about 40% of all wilms tumor cases, but the full map of genetic mutations in wilms tumor is far from clear. Whole genome sequencing and RNA sequencing were performed in 5 pairs of wilms tumor tissues and ad...

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Bibliographic Details
Main Authors: Bai-Hui Liu, Gong-Bao Liu, Bin-Bin Zhang, Jian Shen, Lu-Lu Xie, Xiang-Qi Liu, Wei Yao, Rui Dong, Yun-Li Bi, Kui-Ran Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
Wilms tumor
MUC6
autophagy
β-catenin
whole genome sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.756117/full

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