Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South Africa

Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South Africa

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Human organic cation transporter 1 is primarily expressed in hepatocytes and mediates the electrogenic transport of various endogenous and exogenous compounds, including clinically important drugs. Genetic polymorphisms in the gene coding for human organic cation transporter 1, SLC22A1, are increasi...

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Bibliographic Details
Main Authors: Clifford Jacobs, Brendon Pearce, Mornè Du Plessis, Nisreen Hoosain, Mongi Benjeddou
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2014-04-01
Series:Genetics and Molecular Biology
Subjects:
polymorphism
haplotype
population genetic structure
genotyping
genetic variability
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572014000300006&tlng=en

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