Endometriosis and autoimmunity
Endometriosis is an inflammatory oestrogen-dependent chronic disease and is mainly expressed by pain and increased infertility. Several studies showed an increased prevalence of autoimmune systemic diseases and various autoantibodies in endometriosis. The association of these autoimmune markers and...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Open Exploration Publishing Inc.
2022-02-01
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| Series: | Exploration of Immunology |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/Journals/ei/Article/100334 |
| _version_ | 1819279228621815808 |
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| author | Noémie Abisror Kamila Kolanska Meryem Cheloufi Lise Selleret Emmanuelle d'Argent Gilles Kayem Arsene Mekinian |
| author_facet | Noémie Abisror Kamila Kolanska Meryem Cheloufi Lise Selleret Emmanuelle d'Argent Gilles Kayem Arsene Mekinian |
| author_sort | Noémie Abisror |
| collection | DOAJ |
| description | Endometriosis is an inflammatory oestrogen-dependent chronic disease and is mainly expressed by pain and increased infertility. Several studies showed an increased prevalence of autoimmune systemic diseases and various autoantibodies in endometriosis. The association of these autoimmune markers and diseases could raise the fact that endometriosis is an authentic autoimmune or inflammatory disease and thus could argue for the use of immunomodulatory therapies. Usually, it is considered that the autoantibodies did not directly act in endometrium implants growth, and could be rather implicated in endometriosis-related infertility. The use of immunomodulatory strategies could be an important alternative or additional strategy to the use of hormones and surgery but need prospective well-designed trials. |
| first_indexed | 2024-12-24T00:24:34Z |
| format | Article |
| id | doaj.art-0954e2a07b5e41dca0428e8e2bff0687 |
| institution | Directory Open Access Journal |
| issn | 2768-6655 |
| language | English |
| last_indexed | 2024-12-24T00:24:34Z |
| publishDate | 2022-02-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Immunology |
| spelling | doaj.art-0954e2a07b5e41dca0428e8e2bff06872022-12-21T17:24:28ZengOpen Exploration Publishing Inc.Exploration of Immunology2768-66552022-02-0121253110.37349/ei.2022.00034Endometriosis and autoimmunityNoémie Abisror0Kamila Kolanska1https://orcid.org/0000-0002-7445-5345Meryem Cheloufi2Lise Selleret3https://orcid.org/0000-0003-0205-6828Emmanuelle d'Argent4Gilles Kayem5https://orcid.org/0000-0002-8218-8814Arsene Mekinian6https://orcid.org/0000-0003-2849-3049Sorbonne Université, AP-HP, Hôpital Saint-Antoine, service de Médecine Interne and Inflammation-(DMU i3), 75012 Paris, FranceSorbonne Université, AP-HP, Hôpital Tenon, service de Gynécologie-Obstétrique et Médecine de la Reproduction, Université Paris 06, UMRS-938, 75020 Paris, France; GRC-6 Centre Expert En Endométriose (C3E), Sorbonne Université, UMRS-938, 75020 Paris, FranceSorbonne Université, AP-HP, Hôpital Trousseau, service d’Obstétrique, Université Paris 06, 75012 Paris, FranceSorbonne Université, AP-HP, Hôpital Tenon, service de Gynécologie-Obstétrique et Médecine de la Reproduction, Université Paris 06, UMRS-938, 75020 Paris, France; GRC-6 Centre Expert En Endométriose (C3E), Sorbonne Université, UMRS-938, 75020 Paris, FranceSorbonne Université, AP-HP, Hôpital Tenon, service de Gynécologie-Obstétrique et Médecine de la Reproduction, Université Paris 06, UMRS-938, 75020 Paris, France; GRC-6 Centre Expert En Endométriose (C3E), Sorbonne Université, UMRS-938, 75020 Paris, FranceSorbonne Université, AP-HP, Hôpital Trousseau, service d’Obstétrique, Université Paris 06, 75012 Paris, FranceSorbonne Université, AP-HP, Hôpital Saint-Antoine, service de Médecine Interne and Inflammation-(DMU i3), 75012 Paris, FranceEndometriosis is an inflammatory oestrogen-dependent chronic disease and is mainly expressed by pain and increased infertility. Several studies showed an increased prevalence of autoimmune systemic diseases and various autoantibodies in endometriosis. The association of these autoimmune markers and diseases could raise the fact that endometriosis is an authentic autoimmune or inflammatory disease and thus could argue for the use of immunomodulatory therapies. Usually, it is considered that the autoantibodies did not directly act in endometrium implants growth, and could be rather implicated in endometriosis-related infertility. The use of immunomodulatory strategies could be an important alternative or additional strategy to the use of hormones and surgery but need prospective well-designed trials.https://www.explorationpub.com/Journals/ei/Article/100334endometriosisautoimmune diseasesimmunomodulation |
| spellingShingle | Noémie Abisror Kamila Kolanska Meryem Cheloufi Lise Selleret Emmanuelle d'Argent Gilles Kayem Arsene Mekinian Endometriosis and autoimmunity Exploration of Immunology endometriosis autoimmune diseases immunomodulation |
| title | Endometriosis and autoimmunity |
| title_full | Endometriosis and autoimmunity |
| title_fullStr | Endometriosis and autoimmunity |
| title_full_unstemmed | Endometriosis and autoimmunity |
| title_short | Endometriosis and autoimmunity |
| title_sort | endometriosis and autoimmunity |
| topic | endometriosis autoimmune diseases immunomodulation |
| url | https://www.explorationpub.com/Journals/ei/Article/100334 |
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