Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in China

Abstract Background Changes in the national drug policy always have impact on the drug utilization. In the context of China health care reform, what changes had happened in the trend of drug utilization in public hospitals? Has this change met the expectations of policy design? This study was conduc...

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Main Authors: Xuefeng Xie, Xu Jin, Ling Zhang, Huihui Sun, Aizong Shen, Xiaohui Huang, Yehuan Sun
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Health Services Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12913-018-3614-8
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author Xuefeng Xie
Xu Jin
Ling Zhang
Huihui Sun
Aizong Shen
Xiaohui Huang
Yehuan Sun
author_facet Xuefeng Xie
Xu Jin
Ling Zhang
Huihui Sun
Aizong Shen
Xiaohui Huang
Yehuan Sun
author_sort Xuefeng Xie
collection DOAJ
description Abstract Background Changes in the national drug policy always have impact on the drug utilization. In the context of China health care reform, what changes had happened in the trend of drug utilization in public hospitals? Has this change met the expectations of policy design? This study was conducted to explore the trend of medicine consumption in county public hospitals before and after health care reform, and to provide real-world evidence to help assess the effectiveness of national drug policy. Methods A cross-sectional study was performed to investigate the drug utilization trends of 6 county public hospitals in Anhui Province, which is the first pilot area of China health care reform. Data were collected before and after the implementation of the China National Essential Medicine Policy (NEMP) to analyse the drug utilization indicators, such as the drug utilization constituent ratio, the rate of essential medicine usage and the rate of antibiotic consumption. Results Chemicals are used most frequently and account for 60%~ 70%, followed by oral agents of proprietary Chinese medicine. The results also show increased consumption of Chinese medicine injections (χ 2  = 28.428, P < 0.01). The top 3 chemical medicines consumed were anti-infective drugs (12.92%), cardiovascular system drugs (11.61%), and digestive system drugs (8.42%). For Chinese traditional medicine, the top 3 drugs consumed were internal medicine drugs (66.03%), surgical drugs (8.45%), and gynaecological drugs (7.70%). The total sales amounts of drugs covered by medical insurance are at a high level (all above 80%), whereas essential medicines are less than 50% at almost all county-level medical institutions. Conclusions This study uncovered the changing tendency of medicine usage under the implementation of the reform. Chinese medicine injections and anti-infective drugs have always been a sustained concern of pharmacovigilance. It is noteworthy that although essential medicines are advocated for as a priority for use in the government-run hospital, the consumption proportion of these medicines is lower than expected.
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spelling doaj.art-09573ab31ebf45f8883ac5ac18f9ca442022-12-21T21:58:24ZengBMCBMC Health Services Research1472-69632018-10-0118111010.1186/s12913-018-3614-8Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in ChinaXuefeng Xie0Xu Jin1Ling Zhang2Huihui Sun3Aizong Shen4Xiaohui Huang5Yehuan Sun6Department of Basic and Clinical Pharmacology, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical UniversityDepartment of Basic and Clinical Pharmacology, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical UniversityDepartment of Basic and Clinical Pharmacology, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical UniversityDepartment of Basic and Clinical Pharmacology, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical UniversityDepartment of Pharmacy, Anhui Provincial HospitalDepartment of Basic and Clinical Pharmacology, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical UniversityDepartment of Epidemiology and Health Statistics, School of Public Health, Anhui Medical UniversityAbstract Background Changes in the national drug policy always have impact on the drug utilization. In the context of China health care reform, what changes had happened in the trend of drug utilization in public hospitals? Has this change met the expectations of policy design? This study was conducted to explore the trend of medicine consumption in county public hospitals before and after health care reform, and to provide real-world evidence to help assess the effectiveness of national drug policy. Methods A cross-sectional study was performed to investigate the drug utilization trends of 6 county public hospitals in Anhui Province, which is the first pilot area of China health care reform. Data were collected before and after the implementation of the China National Essential Medicine Policy (NEMP) to analyse the drug utilization indicators, such as the drug utilization constituent ratio, the rate of essential medicine usage and the rate of antibiotic consumption. Results Chemicals are used most frequently and account for 60%~ 70%, followed by oral agents of proprietary Chinese medicine. The results also show increased consumption of Chinese medicine injections (χ 2  = 28.428, P < 0.01). The top 3 chemical medicines consumed were anti-infective drugs (12.92%), cardiovascular system drugs (11.61%), and digestive system drugs (8.42%). For Chinese traditional medicine, the top 3 drugs consumed were internal medicine drugs (66.03%), surgical drugs (8.45%), and gynaecological drugs (7.70%). The total sales amounts of drugs covered by medical insurance are at a high level (all above 80%), whereas essential medicines are less than 50% at almost all county-level medical institutions. Conclusions This study uncovered the changing tendency of medicine usage under the implementation of the reform. Chinese medicine injections and anti-infective drugs have always been a sustained concern of pharmacovigilance. It is noteworthy that although essential medicines are advocated for as a priority for use in the government-run hospital, the consumption proportion of these medicines is lower than expected.http://link.springer.com/article/10.1186/s12913-018-3614-8Drug utilizationHealth care reformRational use of medicinePharmacovigilance
spellingShingle Xuefeng Xie
Xu Jin
Ling Zhang
Huihui Sun
Aizong Shen
Xiaohui Huang
Yehuan Sun
Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in China
BMC Health Services Research
Drug utilization
Health care reform
Rational use of medicine
Pharmacovigilance
title Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in China
title_full Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in China
title_fullStr Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in China
title_full_unstemmed Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in China
title_short Trends analysis for drug utilization in county public hospitals: a sample study of the pilot area of health care reform in China
title_sort trends analysis for drug utilization in county public hospitals a sample study of the pilot area of health care reform in china
topic Drug utilization
Health care reform
Rational use of medicine
Pharmacovigilance
url http://link.springer.com/article/10.1186/s12913-018-3614-8
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